Category: 1008-89-5

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Phenylpyridine, is researched, Molecular C11H9N, CAS is 1008-89-5, about Isolation of Homoleptic Dicationic Tellurium and Monocationic Bismuth Analogues of Non-N-Heterocyclic Carbene Derivatives.Formula: C11H9N.

The first examples of Te analogs of non-N-heterocyclic carbene (non-NHC) derivatives, [(ppy)2Te]·2ClO4, (4·2ClO4), and [(ppy)2Te]·2OTf, (5·2OTf, Hppy = 2-phenylpyridine) are reported by the metathesis reaction of diorganoiodotelluronium(IV) cation, [(ppy)2TeI]·I3, (3·I3), with AgClO4 and AgOTf, resp. The metathesis reaction of ppyTeCl3 (6), with an excess of AgClO4 resulted in the isolation of [ppyTe(μ-O)]2·2ClO4 (8·2ClO4). The reaction of triorganotelluronium(IV) cation [(ppy)3Te]·Br (10·Br), with K2PdCl4 afforded [(ppy)2TeCl]·[(ppy)PdCl2] (11). The generality of the “”ppy”” group on stabilizing other main-group non-NHC analogs has been further established by synthesizing the second example of a Bi analog of a non-NHC derivative, namely, bismuthenium ion, [(ppy)2Bi]·Cl (12·Cl), using the same aryl group. All of the synthesized compounds are unambiguously authenticated by single-crystal X-ray diffraction studies. DFT calculations, natural bond orbital (NBO), atoms in mols. (AIM), and electron localization function (ELF) indicate that the stability of the non-NHC carbenoids relies on the σ-hole participation of the Te/Bi atom with the strong intramol. coordination ability of the pyridyl N atom of the aryl substituent.

There is still a lot of research devoted to this compound(SMILES：C1(C2=CC=CC=C2)=NC=CC=C1)Formula: C11H9N, and with the development of science, more effects of this compound(1008-89-5) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Sulfur(IV)-Mediated Unsymmetrical Heterocycle Cross-Couplings, published in 2020-04-27, which mentions a compound: 1008-89-5, mainly applied to sulfur unsym heterocycle coupling; cross-coupling; heterocycles; sulfur; sulfurane, Electric Literature of C11H9N.

Despite the tremendous utilities of metal-mediated cross-couplings in modern organic chem., coupling reactions involving nitrogenous heteroarenes remain a challenging undertaking – coordination of Lewis basic atoms into metal centers often necessitate elevated temperature, high catalyst loading, etc. Herein, the authors report a sulfur (IV) mediated cross-coupling amendable for the efficient synthesis of heteroaromatic substrates. Addition of heteroaryl nucleophiles to a simple, readily-accessible alkyl sulfinyl (IV) chloride gave a trigonal bipyramidal sulfurane intermediate. Reductive elimination therefrom provides bis-heteroaryl products in a practical and efficient fashion.

If you want to learn more about this compound(2-Phenylpyridine)Electric Literature of C11H9N, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1008-89-5).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: 1008-89-5. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 2-Phenylpyridine, is researched, Molecular C11H9N, CAS is 1008-89-5, about An Efficient Probe of Cyclometallated Phosphorescent Iridium Complex for Selective Detection of Cyanide. Author is Lin, Nan; Ou, Hui-Dan; Xu, Qiyan; Jin, Yan; Deng, Wei; Yao, Zi-Jian.

A cyclometallated phosphorescent iridium-based probe to detect CN- was prepared through a cyanide alcoholize reaction based on the C-N type main ligand and N-N type ancillary ligand (2-Ph pyridine and 1,10-phenanthroline-5-carboxaldehyde, resp.). The efficient probe exhibited good sensitivity in response to CN- in an CH3CN and H2O (95/5) mixture within a 1.23 μM detection limit. The response of PL is directly in line with the concentration of CN- from 0 to 2.0 equivalent The PL investigation of other reactive anions proved the great selectivity to CN-. Addnl., upon adding 1.0 equivalent of cyanide, the formation of cyanohydrin was correctly elucidated in 1H NMR, FT-IR, and mass spectra studies. The conspicuous results indicate that the iridium complex has the potential possibility of application in other biosystems related to CN-.

If you want to learn more about this compound(2-Phenylpyridine)HPLC of Formula: 1008-89-5, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1008-89-5).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Tailor, Sanita B.; Manzotti, Mattia; Smith, Gavin J.; Davis, Sean A.; Bedford, Robin B. researched the compound: 2-Phenylpyridine( cas:1008-89-5 ).Safety of 2-Phenylpyridine.They published the article 《Cobalt-Catalyzed Coupling of Aryl Chlorides with Aryl Boron Esters Activated by Alkoxides》 about this compound( cas:1008-89-5 ) in ACS Catalysis. Keywords: biaryl preparation transmetalation key step kinetics linear free energy; aryl chloride boron reagent alkoxide Suzuki coupling cobalt catalyst. We’ll tell you more about this compound (cas:1008-89-5).

The cobalt-catalyzed Suzuki biaryl cross-coupling of aryl chloride substrates with aryl boron reagents, activated with more commonly used bases, remained a significant unmet challenge in the race to replace platinum group metal catalysts with Earth-abundant metal alternatives. This highly desirable process can be realized using alkoxide bases, provided the right counterion is employed, strict stoichiometric control of the base is maintained with respect to the aryl boron reagent, and the correct boron ester is selected. Potassium tert-butoxide works well, but any excess of the base first inhibits and then poisons the catalyst. Lithium tert-butoxide performs very poorly, while even catalytic amounts of lithium additives also poison the catalyst. Meanwhile, a neopentane diol-based boron ester is required for best performance. As well as delivering this sought-after transformation, a detailed mechanistic and computational investigations to probe the possible mechanism of the reaction has been discussed and explains the unexpected exptl. observations.

If you want to learn more about this compound(2-Phenylpyridine)Safety of 2-Phenylpyridine, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1008-89-5).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Blood-Brain Barrier Penetrating Luminescent Conjugates Based on Cyclometalated Platinum(II) Complexes, published in 2020-11-18, which mentions a compound: 1008-89-5, mainly applied to platinum phenylpyridine benzofuranylpyridine benzotiophenylpyridine imidazole derivative complex preparation luminescence; cytotoxicity platinum phenylpyridine benzofuranylpyridine benzotiophenylpyridine imidazole derivative, Name: 2-Phenylpyridine.

Herein we report on the synthesis, structural characterization and photophys. properties of cyclometalated Pt(II) complexes [Pt(N^C)(PPh2(C6H4COOH))Cl] (where N^C ligands are 2-phenylpyridine, (2-benzofuran-3-yl)pyridine, and (2-benzo[b]tiophen-3-yl)pyridine) and their conjugates with the histidine-containing RRRRRRRRRRHVLPKVQA peptide. This peptide contains the RHVLPKVQA sequence, which is responsible for antiamyloid activity, and the Arg9 RRRRRRRRR domain, which shows improved translocation through cell membranes. The chem. underpinning the conjugation is regioselective complexation between Pt(II) complexes and histidine residue in the peptide. The prepared conjugates have been characterized using high-resolution mass spectrometry and NMR spectroscopy. It was shown that the conjugates are easily soluble in aqueous media and display emission band profiles essentially similar to those of the starting complexes but considerably higher luminescence quantum yield and much longer phosphorescence lifetime. MTT assay on HeLa cell culture revealed no cytotoxicity up to 10μM after 24 h of incubation. Ex vivo and in vivo neuroimaging experiments on both wild and amyloid peptide expressing strains of Drosophila melanogaster revealed that the conjugates penetrate the blood-brain barrier and are evenly distributed throughout the brain independently of the strain used.

If you want to learn more about this compound(2-Phenylpyridine)Name: 2-Phenylpyridine, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1008-89-5).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1008-89-5, is researched, Molecular C11H9N, about Fabrication and Application of Graphene Supported Diimine-Palladium Complex Catalyst for Organic Synthesis, the main research direction is diimine anchored graphene oxide supported palladium complex preparation; biaryl preparation; aryl bromide arylboronic acid Suzuki palladium nanocatalyst; azole aryl bromide CH arylation palladium nanocatalyst.Formula: C11H9N.

In this paper, a diimine palladium complex with suitable steric hindrance of iso-Pr groups and electron supply provided excellent protection for palladium active centers was synthesized and anchored on graphene oxide (GO) to obtain a reusable heterogeneous catalyst (Pd-DI@GO). The XPS results confirmed the effective loading of palladium and the interaction between palladium and ligand. The ICP-AES data verified the Pd content of catalyst was 5.04 wt% and confirmed extremely small amount Pd leaching in Suzuki reaction (<1 ppm). The Pd-DI@GO could catalyze Suzuki reaction and C-H direct arylation reaction of aryl bromides and arylboronic acids/heterocycles to afford biaryls R-R1 [R = Ph, 4-MeC6H4, 2-MeOC6H4, etc.; R1 = Ph, 1-naphthyl, 2-pyridyl, etc] and R2-R3 [R2 = Ph, 4-ClC6H4, 4-tBuC6H4, etc. R3 = 2,4-(Me)2-5-thiazolyl, 2-Me-5-thiazolyl, 4-Me-5-thiazolyl] with high yields. Notably, the Pd-DI@GO could be recycled after Suzuki reaction via filtration or centrifugation easily, presented a yield above 90% for the 4th run. Here is a brief introduction to this compound(1008-89-5)Formula: C11H9N, if you want to know about other compounds related to this compound(1008-89-5), you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Related Products of 1008-89-5. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Phenylpyridine, is researched, Molecular C11H9N, CAS is 1008-89-5, about AIBN for Ru-catalyzed meta-CAr-H alkylation. Author is Yang, Suling; Yan, Bingxu; Zhong, Lei; Jia, Chunqi; Yao, Dan; Yang, Chunli; Sun, Kai; Li, Gang.

The meta-CAr-H alkylation of arenes with radicals produced from AIBN in the presence of a RuCl3 catalyst was presented. This development not only confirmed that ruthenium-catalyzed meta-CAr-H bond functionalization was a radical process, but also provided an efficient and practical strategy for the preparation of aromatic compounds containing a nitrile group, which were prevalent in a diverse range of biol. active mols. and other functional materials.

Here is a brief introduction to this compound(1008-89-5)Related Products of 1008-89-5, if you want to know about other compounds related to this compound(1008-89-5), you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 2-Phenylpyridine. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Phenylpyridine, is researched, Molecular C11H9N, CAS is 1008-89-5, about Visible-Light-Driven C4-Selective Alkylation of Pyridinium Derivatives with Alkyl Bromides.

Reported herein is a general strategy for the photochem. cross-coupling between N-amidopyridinium salts and various alkyl bromides under photocatalyst-free conditions, granting facile access to various C4-alkylated pyridines. This approach exploits the intriguing photochem. activity of electron donor-acceptor (EDA) complexes between N-amidopyridinium salts and bromide, which provides a photoactive handle capable of generating silyl radicals and driving the alkylation process. The robustness of this protocol was further demonstrated by the late-stage functionalization of complex compounds, e.g., dehydroepiandrosterone and oxaprozin, under mild and metal-free conditions.

Here is a brief introduction to this compound(1008-89-5)Quality Control of 2-Phenylpyridine, if you want to know about other compounds related to this compound(1008-89-5), you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles