Category: 110-52-1

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1,4-Dibromobutane(SMILESS: BrCCCCBr,cas:110-52-1) is researched.SDS of cas: 60827-45-4. The article 《Preparation of functionalized diallylimidazole ionic liquid and its application in conversion of D-fructose into HMF》 in relation to this compound, is published in Journal of Molecular Liquids. Let’s take a look at the latest research on this compound (cas:110-52-1).

A kind of functionalized diallylimidazole ionic liquids (CnDAIMF) was synthesized and applied in the dehydration of D-fructose to produce 5-HMF under the microwave radiation. The target ILs existed in a highly centrally sym., and crystalline state at room temperature, with a good thermal stability up to 300° (HTD ≥ 340°). In the experiments of conversion D-fructose to 5-HMF, 5-HMF could be obtained via the catalysis of diallylimidazole IL whether in water or DMSO. The catalytic performance of these ILs was not much different from that of solid acid (like camphor sulfonic acid or solid carbon sulfonic acid), and which was higher than that of the monoimidazole hexafluorophosphate or imidazole class bromine salt, but there were no obvious changes can be found with the variation of carbon chain length between imidazole rings in diallylimidazole IL. The effects of temperature and solvent on the reaction were more significant. The optimized yield of 5-HMF was 52.59% at 185° in a water-C2DAIMF solvent (t = 10 min), while 73.71% at 195° in DMSO-C2DAIMF solvent. Furthermore, six CnDAIMF have a considerable effect on the conversion in water and 5-HMF yield of about 50% could be obtained, which is satisfactory compared with other similar processes, especially in the microwave system of aqueous solution Therefore, this process may be benefit for many researches and applications related to functionalized ionic liquid research and biomass conversion applications.

Here is just a brief introduction to this compound(110-52-1)COA of Formula: C4H8Br2, more information about the compound(1,4-Dibromobutane) is in the article, you can click the link below.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of Molecular Liquids called Ionic macromolecules based on non-halide counter anions for super prevention of copper corrosion, Author is Luo, Weiping; Zhang, Shengtao; Wang, Xinchao; Gao, Fang; Li, Hongru, which mentions a compound: 110-52-1, SMILESS is BrCCCCBr, Molecular C4H8Br2, Reference of 1,4-Dibromobutane.

New non-halide counter anions based ionic macromols. (IMs) were synthesized by the ionic exchange method. The mol. aggregates of the target IMs were formed in H2SO4 medium. The evolving concentrations and time showed a remarkable influence on the formation of the IMs aggregates. Copper surface could be adsorbed by the IMs, which were confirmed by the SEM as well as AFM imaging. The contacting angles suggest that the adsorption layers of the IMs on metal surface could be composed by the inner hydrophobic film and the outer hydrophilic film. The IMs-copper bonding was further demonstrated by different means including FT-IR and XPS. The electrochem. survey suggested that the IMs adsorption layers inhibited copper corrosion in H2SO4 solution, and the peak efficiency of corrosion inhibition reached over 99%. In addition, the mixed chemisorption and physisorption of the IMs to copper is reveled by the Langmuir isotherms.

Compound(110-52-1)Reference of 1,4-Dibromobutane received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1,4-Dibromobutane), if you are interested, you can check out my other related articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 1,4-Dibromobutane, is researched, Molecular C4H8Br2, CAS is 110-52-1, about Regioselective Hydroalkylation of Vinylarenes by Cooperative Cu and Ni Catalysis.COA of Formula: C4H8Br2.

Disclosed here is a dual copper and nickel catalytic system with a silyl hydride source for promoting the linear selective hydroalkylation of vinylarenes ArCHCH2 (Ar = 4-fluorophenyl, pyridin-2-yl, 2-methyl-1,3-benzoxazol-6-yl, etc.). This carbon-carbon bond-forming protocol is applied to couple a variety of functionalized vinylarenes with alkyl halides RX (R = phenylethyl, cyclohexyl, 3-(2H-1,3-benzodioxol-5-yloxy)propyl, etc.; X = Br, I) applying a nickel(II) NNN pincer complex in the presence of an NHC-ligated copper catalyst. This combination allows for a 1 mol% loading of the nickel catalyst leading to turnover numbers of up to 72. Over 40 examples are presented, including applications for pharmaceutical diversification. Labeling experiments demonstrated the regioselectivity of the reaction and revealed that the copper catalyst plays a crucial role in enhancing the rate for formation of the reactive linear alkyl nickel complex. Overall, the presented work provides a complimentary approach for hydroalkylation reactions, while providing a preliminary mechanistic understanding of the cooperativity between the copper and nickel complexes.

Compound(110-52-1)COA of Formula: C4H8Br2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1,4-Dibromobutane), if you are interested, you can check out my other related articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C4H8Br2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,4-Dibromobutane, is researched, Molecular C4H8Br2, CAS is 110-52-1, about Preparation and polymerization analysis of poly(alkenyl-based di-ionic ionic liquid). Author is Guo, Yanni; Tang, Yining; He, Deliang; Liu, Mengli; Pan, Rong; Dong, Wei; Ma, Li.

In this study, bis-imidazole-containing ionic liquids (VDILs) featuring halide counter anions and substituted with different numbers of alkenyl groups were designed and synthesized. The VDILs were further subjected to a one-pot free radical polymerization in aqueous solution, forming hydrophobic PVDILs. GPC, FT-IR, XPS, and XRD were performed to determine the influence of the number and position of the alkenyl groups in the VDIL monomers on the mol. weight, mol. weight distribution, and polymeric structure of the PVDILs. The GPC results showed that the position of the alkenyl groups had a significant influence on the mol. weight of the PVDILs. The linker alkenyl group in the VDIL monomer was easier to polymerize than the alkenyl group connected to the N(1) atom of the imidazole ring of the VDIL due to the steric bulk of the counter anions, which mitigated cross-polymerization of the vinyl groups. As the interconnected polymeric network was being formed, the steric bulk of the anions hindered chain growth, resulting in a lower-than-expected mol. weight of PVDIL-3. XPS and FT-IR results indicated that there were still a certain number of alkenyl groups that remained in the PVDIL-1 and PVDIL-3 structures after polymerization, with the PVDIL-3 sample containing 3% more alkenyl groups than PVDIL-2. This study demonstrates a new method for the polymerization of alkenyl-based DILs and provides a foundation for the application of PDILs.

Compound(110-52-1)Formula: C4H8Br2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(1,4-Dibromobutane), if you are interested, you can check out my other related articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1,4-Dibromobutane, is researched, Molecular C4H8Br2, CAS is 110-52-1, about Design and synthesis of gradient-refractive index isosorbide-based polycarbonates for optical uses, the main research direction is design refractive index isosorbide polycarbonate.Quality Control of 1,4-Dibromobutane.

The synthesis of bio-based polymers using renewable bio-monomers have received extensive research attention to meet the concept of environmental sustainability. Isosorbide (ISB) derived from biomass is commonly used in the polycarbonate industry as an alternative to bisphenol A (BPA) because it is green, non-toxic, and more widely available. Compared to BPA-based polycarbonate, isosorbide-based polycarbonate has excellent properties such as high transparency, easy coloration, and outstanding rigidity. However, the naturally low refractive index of isosorbide triggers the latter to fall outside the threshold of optical applications. In order to further improve the refractive index of isosorbide-based polycarbonate without affecting its transparency and rigidity, a copolymerization scheme of bisphenol monomers (BPs) with isosorbide is proposed in this work. A series of isosorbide-bisphenol copolycarbonates were synthesized by a melt polycondensation process using ionic liquid 1,4-(1,4-diazabicyclo[2.2.2]octane)butyl dibromide ([C4(DABCO)2][Br]2) as the catalyst. As expected, the monomer structure had significant effect on the optical property and mol. weight of the copolycarbonates, the monomer bis(p-hydroxyphenyl) ether (BPO) had better reactivity among the screened seven monomers resulting in relatively higher mol. weight Moreover, poly(BPO-co-ISB carbonate) (POIC) using BPO as the monomer exhibited a high Abbe number (vd = 39.7), low yellowness index (YI = 0.93), and a higher refractive index (nd = 1.536), which was much higher than poly(isosorbide carbonate) (1.496). Therefore, a series of POICs were further prepared to investigate the effect of BPO content on the optical, thermal, mech., and hydrophobic properties of the materials. The results showed that the copolymers POICs had higher refractive indexes (1.511-1.573), better thermal stability, flexibility, hydrophobicity and processing-friendly glass transition temperature (Tg) and pencil hardness, and thus are expected to be sustainable materials for optical lenses.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1,4-Dibromobutane(SMILESS: BrCCCCBr,cas:110-52-1) is researched.Safety of 1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione. The article 《One-Step Synthesis of Lignin-Based Triblock Copolymers as High-Temperature and UV-Blocking Thermoplastic Elastomers》 in relation to this compound, is published in Angewandte Chemie, International Edition. Let’s take a look at the latest research on this compound (cas:110-52-1).

This work utilizes frustrated Lewis pairs consisting of tethered bis-organophosphorus superbases and a bulky organoaluminum to furnish the highly efficient synthesis of well-defined triblock copolymers via one-step block copolymerization of lignin-based syringyl methacrylate and Bu acrylate, through di-initiation and compounded sequence control. The resulting thermoplastic elastomers (TPEs) exhibit microphase separation and much superior mech. properties (elongation at break up to 2091%, tensile strength up to 11.5 MPa, and elastic recovery up to 95% after 10 cycles) to those of Me methacrylate-based TPEs. More impressively, lignin-based tri-BCPs can maintain TPEs properties up to 180°C, exhibit high transparency and nearly 100% UV shield, suggesting potential applications in temperature-resistant and optical devices.

As far as I know, this compound(110-52-1)COA of Formula: C4H8Br2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 110-52-1, is researched, SMILESS is BrCCCCBr, Molecular C4H8Br2Journal, Article, Bioorganic & Medicinal Chemistry Letters called Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders, Author is Bhumireddy, Archana; Bandaru, N. V. M. Rao; Raghurami Reddy, B.; Gore, Suraj T.; Mukherjee, Subhendu; Balasubramanian, Wesley Roy; Sumanth Kumar, V.; Alapati, Krishna Satya; Venkata Gowri Chandra Sekhar, Kondapalli; Nellore, Kavitha; Abbineni, Chandrasekhar; Samajdar, Susanta, the main research direction is phenyl thiazole ligand binding domain ARV7 degrader; 22Rv1; AR-V7; CRPC; Degrader; PROTAC.SDS of cas: 110-52-1.

Multiple Splice variants of AR have been reported in the past few years. These splice variants are upregulated in most cases of CRPC resulting in poor prognosis. Most of these variants lack the ligand binding domain (LBD) but still bind to DNA resulting in constitutive activation of downstream targets. The AR-V7 splice variant has been characterized extensively and current clin. trials in CRPC are exploring the use of AR-V7 as a biomarker. New therapeutic mols. that selectively target AR-V7 are also being explored. However, there is a dearth of information available on the selectivity, phenotypic responses in AR-V7 dependent cell lines and pharmacokinetic properties of such mols. Using our proprietary computational algorithms and rational SAR optimization, we have developed a potent and selective AR-V7 degrader from a known AR DNA binding domain (DBD) binder. This mol. effectively degraded AR-V7 in a CRPC cell line and demonstrated good oral bioavailability in mouse PK studies. This tool compound can be used to evaluate the pharmacol. effects of AR-V7 degraders. Further exploration of SAR can be pursued to develop more optimized lead compounds

As far as I know, this compound(110-52-1)SDS of cas: 110-52-1 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1,4-Dibromobutane, is researched, Molecular C4H8Br2, CAS is 110-52-1, about Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade, the main research direction is dioxane thiane oxathiane preparation diastereoselective regioselective; alkyne aldehyde hydroacylation conjugate addition tandem rhodium.Reference of 1,4-Dibromobutane.

Rhodium-catalyzed hydroacylation using alkynes substituted with pendant nucleophiles, delivers linear α,β-unsaturated enone intermediates with excellent regioselectivity. These adducts are used to construct a broad range of diversely substituted, saturated O-, N- and S-heterocycles in a one-pot process. Judicious choice of cyclisation conditions enabled isolation of O-heterocycles with high levels of diastereoselectivity. A variety of derivatization reactions are also performed, generating functionalized hydroacylation products. This sequence serves as a general approach for the synthesis of fully saturated heterocycles.

From this literature《Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade》,we know some information about this compound(110-52-1)Reference of 1,4-Dibromobutane, but this is not all information, there are many literatures related to this compound(110-52-1).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Huang, Mingming; Hu, Jiefeng; Krummenacher, Ivo; Friedrich, Alexandra; Braunschweig, Holger; Westcott, Stephen A.; Radius, Udo; Marder, Todd B. published an article about the compound: 1,4-Dibromobutane( cas:110-52-1,SMILESS:BrCCCCBr ).Related Products of 110-52-1. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:110-52-1) through the article.

A practical and direct method was developed for the production of versatile alkyl boronate esters via transition metal-free borylation of primary and secondary alkyl sulfones. The key to the success of the strategy is the use of bis(neopentyl glycolato) diboron (B2neop2), with a stoichiometric amount of base as a promoter. The practicality and industrial potential of this protocol are highlighted by its wide functional group tolerance, the late-stage modification of complex compounds, no need for further transesterification, and operational simplicity. Radical clock, radical trap experiments, and EPR studies were conducted which show that the borylation process involves radical intermediates.

There is still a lot of research devoted to this compound(SMILES：BrCCCCBr)Related Products of 110-52-1, and with the development of science, more effects of this compound(110-52-1) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 110-52-1, is researched, Molecular C4H8Br2, about Ultrafast electronic dynamics and vibrational dynamics of SWCNT under alkylation and annealing, the main research direction is carbon nanotube alkylation annealing ultrafast electronic vibrational transient absorption.Reference of 1,4-Dibromobutane.

Using ultrashort visible pulse laser, the authors have performed transient absorption spectroscopy to study the electronic relaxation and vibrational dynamics for 3 single-wall C nanotube (SWCNT) samples of nonsubstituted SWCNT, alkylated SWCNT, and annealed alkylated SWCNT. Estimated lifetimes of ∼100 fs and ∼1 ps can be assigned to intraband and interband relaxation processes, resp. Compared with the nonsubstituted sample, the intraband transition rate is 7% smaller for the alkylated sample and nearly equal to the annealed alkylated sample within 2%. It implies that the intraband relaxation rate is not affected by alkylation itself but inhibited by excess chem. modification. Conversely, the interband relaxation rate shows no difference between the 3 samples. Short-time Fourier transform anal. of the measured traces of pump-probe delay dependent difference absorbance visualizes the change of mol. vibration frequency reflecting the energy transfer from (6,5)-SWCNT to (6,4)-SWCNT and the mol. structure change during the interband transition.

There is still a lot of research devoted to this compound(SMILES：BrCCCCBr)Reference of 1,4-Dibromobutane, and with the development of science, more effects of this compound(110-52-1) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles