Category: 120-14-9

An article Synthesis, characterization and antichagasic evaluation of thiosemicarbazones prepared from chalcones and dibenzalacetones WOS:000632867700003 published article about CHAGAS-DISEASE; BENZNIDAZOLE; POSACONAZOLE; CHALLENGES; COMPLEXES; DESIGN in [da Silva, Aline Alves; Valle, Marcelo Siqueira] Univ Fed Sao Joao Del Rei, Dept Ciencias Nat, BR-36301160 Sao Joao Del Rei, MG, Brazil; [Maia, Pedro Ivo da Silva] Univ Fed Triangulo Mineiro, Dept Quim, BR-38025440 Uberaba, MG, Brazil; [Lopes, Carla Duque; de Albuquerque, Sergio] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Ave Cafes S-N, BR-14040903 Ribeirao Preto, SP, Brazil; [Lopes, Carla Duque; de Albuquerque, Sergio] Univ Sao Paulo, USP, FCFRP, Ave Cafes S-N, BR-14040903 Ribeirao Preto, SP, Brazil; [Lopes, Carla Duque] Ctr Univ Estacio Ribeirao Preto, Abraao Issa Halach St 980, BR-14096160 Ribeirao Preto, SP, Brazil in 2021, Cited 28. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. COA of Formula: C9H10O3

Chagas disease is a neglected disease, being one of the leading causes of death from infectious diseases. In view of the severity of this pathology, this work describes the synthesis of new thiosemicarbazones derived from chalcones and dibenzalacetones as potential drugs for the treatment of this disease. The structures of all compounds were elucidated by infrared (IR) and nuclear magnetic resonance (H-1 and C-13 NMR) spectroscopies. The chalcone derived thiosemicarbazones 10-14 were tested against the intracellular amastigote form of the protozoan Trypanosoma cruzi and had their cytotoxicity assessed using LLC-MK2 cells. The compound 10 (IC50 = 12.25 mu M) presented the best activity when compared with the standard drug benznidazole (IC50 = 5.64 mu M). (C) 2021 Elsevier B.V. All rights reserved.

COA of Formula: C9H10O3. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N ‘-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage WOS:000667581800045 published article about ALPHA-LIPOIC ACID; NF-KAPPA-B; INDUCED NEPHROTOXICITY; INDUCED HEPATOTOXICITY; OXIDATIVE STRESS; STAT3; ANTIOXIDANT; DESIGN; INTERLEUKIN-6; CYTOKINES in [Razak, Suhail; Afsar, Tayyaba; Abulmeaty, Mahmoud; Almajwal, Ali; Al Disi, Dara] King Saud Univ, Coll Appl Med Sci, Dept Community Hlth Sci, Riyadh, Saudi Arabia; [Bibi, Nousheen; Inam, Anam] Shaheed Benazir Bhutto Women Univ, Dept Bioinformat, Peshawar, Pakistan; [Qamar, Wajhul] King Saud Univ, Coll Pharm, Dept Pharmocol & Toxicol, Cent Lab, Riyadh 11451, Saudi Arabia; [Bhat, Mashooq Ahmad] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia; [Shabbir, Maria] Natl Univ Sci & Technol, Atta Ur Rahman Sch Appl Biosci, Islamabad, Pakistan in 2021.0, Cited 76.0. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9. COA of Formula: C9H10O3

Cisplatin is an efficient anticancer drug against various types of cancers however, its usage involves side effects. We investigated the mechanisms of action of indole derivative, 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N’-[(E)-(3-nitrophenyl) methylidene] acetohydrazide (MMINA) against anticancer drug (cisplatin) induced organ damage using a rodent model. MMINA treatment reversed Cisplatin-induced NO and malondialdehyde (MDA) augmentation while boosted the activity of glutathione peroxidase (GPx), and superoxide dismutase (SOD). The animals were divided into five groups (n=7). Group1: Control (Normal) group, Group 2: DMSO group, Group 3: cisplatin group, Group 4: cisplatin+MMINA group, Group 5: MMINA group. MMINA treatment normalized plasma levels of biochemical enzymes. We observed a significant decrease in CD4(+)COX-2, STAT3, and TNF-alpha cell population in whole blood after MMINA dosage. MMINA downregulated the expression of various signal transduction pathways regulating the genes involved in inflammation i.e. NF-kappa B, STAT-3, IL-1, COX-2, iNOS, and TNF-alpha. The protein expression of these regulatory factors was also downregulated in the liver, kidney, heart, and brain. In silico docking and dynamic simulations data were in agreement with the experimental findings. The physiochemical properties of MMINA predicted it as a good drug-like molecule and its mechanism of action is predictably through inhibition of ROS and inflammation.

COA of Formula: C9H10O3. Welcome to talk about 120-14-9, If you have any questions, you can contact Razak, S; Afsar, T; Bibi, N; Abulmeaty, M; Qamar, W; Almajwal, A; Inam, A; Al Disi, D; Shabbir, M; Bhat, MA or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article Sustainable aromatic polyesters with 1,5-disubstituted indole units WOS:000649534900037 published article about TEREPHTHALATE POLYESTERS; CATALYTIC CONVERSION; THERMAL-PROPERTIES; BUILDING-BLOCKS; BIFURAN DIESTER; VANILLIC ACID; DEGRADATION; CRYSTALLIZATION; COPOLYESTERS; BIOPOLYMER in [Wang, Ping; Zhang, Baozhong] Lund Univ, Ctr Anal & Synth, POB 124, SE-22100 Lund, Sweden in 2021.0, Cited 76.0. Category: indole-building-block. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

This work aims to unravel the impact of disubstitution patterns on the physical properties and processing characteristics of indole-based aromatic polyesters. A series of hydroxyl-carboxylate (AB-type) monomers with 1,5-disubstituted indole and 3-6 methylene units was conveniently synthesized and used in bulk polycondensation to yield the corresponding polyesters with decent molecular weight. These new monomers and polyesters showed enhanced thermal stability compared to the previously reported monomers and polyesters with a 1,3-disubstituted indole structure. According to DSC results, these polyesters showed tunable glass transition temperatures (T-g similar to 57-80 degrees C), depending on the length of the aliphatic methylene units. DSC and WAXD measurements revealed that these polymers did not crystalize from melt, but the ones with 3 or 5 methylene units per repeating unit crystalized from solution. Finally, we demonstrated that the new polyesters with 1,5-disubstituted indole units could be crosslinked using sustainable aromatic aldehyde, which could further enhance their thermal properties.

Category: indole-building-block. Welcome to talk about 120-14-9, If you have any questions, you can contact Wang, P; Zhang, BZ or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. Authors Kukkonen, E; Lahtinen, E; Myllyperkio, P; Haukka, M; Konu, J in ROYAL SOC CHEMISTRY published article about in [Kukkonen, Esa; Lahtinen, Elmeri; Haukka, Matti; Konu, Jari] Univ Jyvaskyla, Dept Chem, POB 35, FI-40014 Jyvaskyla, Finland; [Myllyperkio, Pasi] Univ Jyvaskyla, Nanosci Ctr, POB 35, FI-40014 Jyvaskyla, Finland in 2021, Cited 46. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Series of highly polar stilbene (1a-e), diphenylbutadiene (2a-c) and phenylethenyIthiophene (3a-c) derivatives were prepared via Horner-Wadsworth-Emmons method with a view to produce new and efficient materials for second harmonic generation (SHG) in the solid-state. The single-crystal X-ray structures of compounds 1-3 reveal extensive polymorphism and a peculiar photodimerization of the 2-chloro-3,4-dimethoxy-4′-nitrostilbene derivative 1a to afford two polymorphs of tetra-aryl cyclobutane 4. The stilbene congeners 2-chloro-3,4-dimethoxy-4′-nitrostilbene (1a. non-centro), 5-bromo-2-hydroxy-3-nitro-4′-nitrostilbene (1b) and 4-dimethylamino-4′-nitrostilbene (1e), as well as 4′-fIuoro-4 ”-nitro-1,4-diphenyl-1,3-butadiene (2a) present the ideal, non-centrosymmetric arrangement of the chromophores for nonlinear optical (NLO) activity. Compounds lb and 2a exhibit only relatively Low intensity for second harmonic generation (0.04 and 0.18 times that of urea reference, respectively), while the stilbene polymorph 1a.non-centro shows NLO activity of over 32 times that of urea. In addition, the conjugated diaromatic compounds 1-3 display fluorescence behaviour in CH2Cl2 solutions with the exception of stilbene derivative 1b.

Application In Synthesis of 3,4-Dimethoxybenzaldehyde. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors Pitucha, M; Korga-Plewko, A; Czylkowska, A; Rogalewicz, B; Drozd, M; Iwan, M; Kubik, J; Humeniuk, E; Adamczuk, G; Karczmarzyk, Z; Fornal, E; Wysocki, W; Bartnik, P in MDPI published article about in [Pitucha, Monika; Drozd, Monika] Med Univ Lublin, Fac Pharm, Independent Radiopharm Unit, PL-20093 Lublin, Poland; [Korga-Plewko, Agnieszka; Kubik, Joanna; Humeniuk, Ewelina; Adamczuk, Grzegorz] Med Univ Lublin, Fac Pharm, Independent Med Biol Unit, PL-20093 Lublin, Poland; [Czylkowska, Agnieszka; Rogalewicz, Bartlomiej] Lodz Univ Technol, Fac Chem, Inst Gen & Ecol Chem, Zeromskiego 116, PL-90924 Lodz, Poland; [Iwan, Magdalena] Med Univ Lublin, Fac Pharm, Chair & Dept Toxicol, PL-20093 Lublin, Poland; [Karczmarzyk, Zbigniew; Wysocki, Waldemar; Bartnik, Paulina] Siedlce Univ Nat Sci & Humanities, Fac Sci, 3 Maja 54, PL-08110 Siedlce, Poland; [Fornal, Emilia] Med Univ Lublin, Fac Med, Chair & Dept Pathophysiol, PL-20090 Lublin, Poland in 2021.0, Cited 50.0. Name: 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

A series of thiosemicarbazone derivatives was prepared and their anti-tumor activity in vitro was tested. The X-ray investigation performed for compounds T2, T3 and T5 confirmed the synthesis pathway and assumed molecular structures of analyzed thiosemicarbazones. The conformational preferences of the thiosemicarbazone system were characterized using theoretical calculations by AM1 method. Selected compounds were converted into complexes of Cu (II) ions. The effect of complexing on anti-tumor activity has been investigated. The copper(II) complexes, with Schiff bases T1, T10, T12, T13, and T16 have been synthesized and characterized by chemical and elemental analysis, FTIR spectroscopy and TGA method. Thermal properties of coordination compounds were studied using TG-DTG techniques under dry air atmosphere. G361, A375, and SK-MEL-28 human melanoma cells and BJ human normal fibroblast cells were treated with tested compounds and their cytotoxicity was evaluated with MTT test. The compounds with the most promising anti-tumour activity were then selected and their cytotoxicity was verified with cell cycle analysis and apoptosis/necrosis detection. Additionally, DNA damages in the form of a basic sites presence and the expression of oxidative stress and DNA damage response genes were evaluated. The obtained results indicate that complexation of thiosemicarbazone derivatives with Cu (II) ions improves their antitumor activity against melanoma cells. The observed cytotoxic effect is associated with DNA damage and G2/M phase of cell cycle arrest as well as disorders of the antioxidant enzymes expression.

Name: 3,4-Dimethoxybenzaldehyde. Welcome to talk about 120-14-9, If you have any questions, you can contact Pitucha, M; Korga-Plewko, A; Czylkowska, A; Rogalewicz, B; Drozd, M; Iwan, M; Kubik, J; Humeniuk, E; Adamczuk, G; Karczmarzyk, Z; Fornal, E; Wysocki, W; Bartnik, P or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Authors El-Helw, EAE; Morsy, ARI; Hashem, AI in WILEY published article about in [El-Helw, Eman A. E.; Hashem, Ahmed I.] Ain Shams Univ, Fac Sci, Chem Dept, Cairo 11566, Egypt; [Morsy, Alaa R. I.] Agr Res Ctr, Cent Lab Evaluat Vet Biol CLEVB, Cairo, Egypt in 2021.0, Cited 38.0. Recommanded Product: 3,4-Dimethoxybenzaldehyde. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

The hydrazide obtained from furan-2(3H)-one integrated with a quinolin-2(1H)-one core reported previously by our research group was utilized as a building block synthon to obtain some pyrrolone, pyridazinone, oxadiazole, and triazole derivatives through treating with some carbon electrophilic reagents, for example, chloroacetyl chloride, benzoyl chloride, acetic anhydride, carbon disulfide, 3,4-dimethoxybenzaldehyde, and 2-oxoquinolin-3-carbaldehyde to achieve the target heterocycles. The newly synthesized compounds were evaluated as immunomodulator against highly pathogenic avian influenza virus (H5N8). The compounds 1, 11, and 17 displayed the highest potency (100% protection).

Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 3,4-Dimethoxybenzaldehyde

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 3,4-Dimethoxybenzaldehyde. Shashi, R; Begum, NS; Panday, AK in [Shashi, R.; Begum, Noor Shahina] Bangalore Univ, Dept Studies Chem, Bangalore 560056, Karnataka, India; [Panday, Anoop Kumar] Indian Inst Technol, Dept Chem, Bihta 801103, Bihar, India published A Rapid Ultrasound Synthesis of Xanthenediones Catalyzed by Boric acid in Ethanol-Water Medium: Single Crystal, DFT and Hirshfeld Surface Analysis of Two Representative Compounds in 2021, Cited 45. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

A highly versatile and efficient ultrasound promoted synthesis of xanthenedione derivatives is achieved through condensation of dimedone with various aromatic aldehydes using boric acid as catalyst in ethanol-water medium. The advantages of this method being, mild reaction conditions, short reaction time, easy work-up, purification of products by non-chromatographic methods and additionally this method provides excellent yields. Two of the Xanthendiones derivatives 3a and 3b gave good crystals on recrystallization and their molecular structures were confirmed by crystallographic studies. The molecules in the crystal lattice are held together by weak intermolecular C-H center dot center dot center dot O and C-H center dot center dot center dot N interactions. Further insights into these interactions using Hirshfeld surface analysis and DFT/B3LYP studies show that in compound 3a H center dot center dot center dot H (54.7%), O center dot center dot center dot H (18.3%) and in 3b H center dot center dot center dot H (53.7%), O center dot center dot center dot H (17.6%) are the major contributors to the intermolecular interactions which stabilize the crystal structures. In order to determine molecular electrical transport properties, we studied the energy difference between Highest Occupied, HOMO, and Lowest Unoccupied, LUMO orbitals and the HOMO and LUMO energy gap for compounds 3a and 3b was found to be 3.9261 eV and 4.6436 eV respectively. The 2D fingerprint plot provided percentage contribution of each individual atom-to-atom interactions. The Mulliken atomic charges and molecular electrostatic potential on molecular van der Waals surface were calculated to know the electrophilic and nucleophilic regions of the molecular surface. (C) 2020 Elsevier B.V. All rights reserved.

Quality Control of 3,4-Dimethoxybenzaldehyde. Welcome to talk about 120-14-9, If you have any questions, you can contact Shashi, R; Begum, NS; Panday, AK or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

An article A novel method of temporary solidification and extraction of underwater fragile relics in their original state WOS:000589895000001 published article about IN-SITU PRESERVATION; CULTURAL-HERITAGE; CONSOLIDANT; CONSERVATION; MENTHOL in [Chen, Xue-Qiang; Zhang, Bingjian] Zhejiang Univ, Dept Cultural Heritage & Museol, Hangzhou 310028, Peoples R China; [Chen, Xue-Qiang] Ningbo Univ Finance & Econ, Cultural Property Protect Ctr, Ningbo 315175, Peoples R China; [Zhang, Zhiguo] Natl Ctr Underwater Cultural Heritage, Beijing 100192, Peoples R China in 2021.0, Cited 22.0. Formula: C9H10O3. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9

Fragile cultural relics at underwater archaeological sites are difficult to preserve in situ over long time periods due to the effects of a complex and constantly changing surrounding environment. Thus, extracting the relics from water and preserving them in a controllable environment is of primary importance. In this paper, the technology of temporary reinforcement and extraction of underwater fragile relics with veratraldehyde followed by a process of secondary temporary reinforcement using polyethylene glycol (PEG) was studied. After investigating the melting temperature and permeability of PEGs with different molecular weights, we found that PEG-3000 is an excellent candidate as the secondary reinforcing agent for the extracted relics. In the laboratory, combined with veratraldehyde and polypropylene-fiber cloth as temporary underwater strengthening materials, and selected dispersed beaded jewelry and a broken three-dimensional crock as our research subject, we carried out an entire retrieval process-temporary stabilization and secondary temporary reinforcement, to systematically evaluate the technological aspects of safely excavating fragile underwater relics in the original state. After being extracted from water and subjected to secondary temporary reinforcement using PEG-3000, the beaded jewelry and broken crock retained their underwater shape and arrangement completely. The use of secondary reinforcing agent prevents the removal process of veratraldehyde and enclosed sediment from affecting the state of the relics.

Formula: C9H10O3. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Chen, XQ; Zhang, BJ; Zhang, ZG or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Saadati-Moshtaghin, HR; Abbasinohoji, F in [Saadati-Moshtaghin, Hamid Reza] Islamic Azad Univ, Islamshahr Branch, Young Researchers & Elite Club, Islamshahr 19166, Iran; [Abbasinohoji, Fahime] Semnan Univ, Dept Chem, Semnan, Iran published LaMnO3 Supported Ionic Liquid; an Efficient Catalyst for One-Pot Three-Component Synthesis of Tetrahydrobenzo[b]Pyran Derivatives Under Solvent-Free Conditions in 2021, Cited 46. COA of Formula: C9H10O3. The Name is 3,4-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 120-14-9.

A new recyclable nanocatalyst consisting of heteropoly acid grafted on ionic liquid modified LaMnO3 nanoparticles was synthesized and accomplished as an efficient catalyst in condensation reaction for the preparation of tetrahydrobenzo[b]pyrans under solvent-free conditions. In addition, it was clarified that supported heteropoly acid (HPA) is the active site for the catalytic reaction, whereas the LaMnO3, ionic liquid functionalized lanthanum manganite nanoparticles are inactive. Different physicochemical methods such as Fourier transform infrared (FT-IR), X-ray powder diffraction (XRD), and field emission scanning electron microscopy (FESEM) were used to characterize the hybrid nanomaterial. The nanocatalyst reusability was affirmed by the use of five consecutive runs. Compared with the various previously reported catalyst, the new synthesized catalyst was found to be the most efficient with regard to reaction time, yield and ease of catalyst separation.

COA of Formula: C9H10O3. Welcome to talk about 120-14-9, If you have any questions, you can contact Saadati-Moshtaghin, HR; Abbasinohoji, F or send Email.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of 3,4-Dimethoxybenzaldehyde. I found the field of Chemistry very interesting. Saw the article A Palladium-Catalyzed Oxa-(4+4)-Cycloaddition Strategy Towards Oxazocine Scaffolds published in 2021.0, Reprint Addresses Archambeau, A (corresponding author), Ecole Polytech, CNRS, Lab Synth Organ, UMR 7652,ENSTA Paris,IP Paris, F-91128 Palaiseau, France.; Garrec, J (corresponding author), ENSTA Paris, Unite Chim & Proc, IP Paris, F-91120 Palaiseau, France.. The CAS is 120-14-9. Through research, I have a further understanding and discovery of 3,4-Dimethoxybenzaldehyde.

A Pd-catalyzed oxa-(4+4)-cycloaddition between 1-azadienes and (2-hydroxymethyl)allyl carbonates is described. Aurone-derived azadienes furnished polycyclic 1,5-oxazocines in good yields. Interestingly, linear azadienes have also been involved and yielded monocyclic heterocycles with complete regioselectivity. DFT calculations were carried out to gain insight on this observation.

Quality Control of 3,4-Dimethoxybenzaldehyde. About 3,4-Dimethoxybenzaldehyde, If you have any questions, you can contact Scuiller, A; Liu, XY; Cordier, M; Garrec, J; Archambeau, A or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles