1245643-61-1, Methyl 5-chloro-1H-indole-6-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of methyl 5-chloro-1 /-/-indole-6-carboxylate (500 mg, 2.39 mmol), B0C2O (781 mg, 3.58 mmol) and DMAP (58.3 mg, 0.477 mmol) in MeCN (8 mL) was stirred at room temperature for 16 h then concentrated in vacuo. The crude product was purified by fee (24 g, 0-50% EtOAc in isohexane) to return the title compound (737 mg, quant) as a colourless oil, which solidified on standing. LCMS [M+H]+ 310; 1 H NMR (400MHz, DMSO-d6) delta 8.59 (s, 1 H), 7.91 (d, J = 3.1 Hz, 1 H), 7.86 (s, 1 H), 6.77 (dd, J = 3.7, 0.7 Hz, 1 H), 3.88 (s, 3H), 1.63 (s, 9H).
1245643-61-1, As the paragraph descriping shows that 1245643-61-1 is playing an increasingly important role.
Reference：
Patent; CANCER RESEARCH TECHNOLOGY LIMITED; JORDAN, Allan; NEWTON, Rebecca; (174 pag.)WO2017/178844; (2017); A1;,
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