Category: 132098-59-0

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 132098-59-0, is researched, Molecular C19H18N2O2, about NMR Quantification of Hydrogen-Bond-Accepting Ability for Organic Molecules, the main research direction is hydrogen bond accepting ability NMR chem shift.Electric Literature of C19H18N2O2.

The hydrogen-bond-accepting abilities for more than 100 organic mols. are quantified using 19F and 31P NMR spectroscopy with pentafluorobenzoic acid (PFBA) and phenylphosphinic acid (PPA) as com. available, inexpensive probes. Anal. of pyridines and anilines with a variety of electronic modifications demonstrates that changes in NMR shifts can predict the secondary effects that contribute to H-bond-accepting ability, establishing the ability of PFBA and PPA binding to predict electronic trends. The H-bond-accepting abilities of various metal-chelating ligands and organocatalysts are also quantified. The measured Δδ(31P) and Δδp(19F) values correlate strongly with Hammett parameters, pKa of the protonated HBA, and proton-transfer basicity (pKBH+).

After consulting a lot of data, we found that this compound(132098-59-0)Electric Literature of C19H18N2O2 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C19H18N2O2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Catalytic Nucleophilic Allylation Driven by the Water-Gas Shift Reaction.

The ruthenium-catalyzed allylation of aldehydes with allylic pro-nucleophiles was demonstrated to be an efficient means to form carbon-carbon bonds under mild conditions. The evolution of this reaction from the initial serendipitous discovery to its general synthetic scope is detailed, highlighting the roles of water, CO, and amine in the generation of a more complete catalytic cycle. The use of unsym. allylic pro-nucleophiles were shown to give preferential product formation through the modulation of reaction conditions. Both (E)-cinnamyl acetate and vinyl oxirane were efficiently used to form the anti-branched products (up to >20:1 anti/syn) and E-linear products (up to >20:1 E/Z) in high selectivity with aromatic, α,β-unsaturated, and aliphatic aldehydes resp. Attempts to render the reaction enantioselective are highlighted and include enantioenrichment of up to 75:25 for benzaldehyde.

Although many compounds look similar to this compound(132098-59-0)Formula: C19H18N2O2, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Enantioselective reduction of ketones with triethoxysilane catalyzed by chiral bis-oxazoline titanium complexes, the main research direction is arylethanol enantioselective preparation; arylbromoethanol enantioselective preparation; asym reduction aryl ketone bromoketone titanium bisoxazoline catalyst ethoxysilane.Electric Literature of C19H18N2O2.

Chiral bis-oxazoline titanium complexes prepared from a 2:1 mixture of C2 chiral bis-oxazolines such as I, BuLi and titanium salts, catalyze the enantioselective reduction of aryl ketones with triethoxysilane as a stoichiometric reductant. E.g., I is treated with 0.67 equivalent nBuLi at -78° in THF, warmed to 0°, and 0.5 equivalent TiF4 was added and the catalyst solution warmed to room temperature; triethoxysilane and 4-MeOC6H4COCH2Br were added and the mixture was stirred for 96h to give benzeneethanol (R)-II in 53% yield and 80% ee.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Habaue, Shigeki; Seko, Tomoaki; Okamoto, Yoshio researched the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0 ).Computed Properties of C19H18N2O2.They published the article 《Copper(I)-Catalyzed Asymmetric Oxidative Coupling Polymerization of 2,3-Dihydroxynaphthalene Using Bisoxazoline Ligands》 about this compound( cas:132098-59-0 ) in Macromolecules. Keywords: copper bisoxazoline complex polymerization catalyst oxidative coupling; polydihydroxynaphthylene preparation chain structure copper bisoxazoline catalyst. We’ll tell you more about this compound (cas:132098-59-0).

The asym. oxidative coupling polymerization of 2,3-dihydroxynaphthalene with complexes of Cu(I)-bisoxazoline as catalysts under an O2 atmosphere was carried out to produce poly(2,3-dihydroxy-1,4-naphthylene) having a continuous 1,1′-bi-2-naphthol main chain structure. The polymerization with (S)-2,2′-isopropylidenebis(4-phenyl-2-oxazoline) as catalyst ligand at room temperature for 24 h afforded a methanol-insoluble polymer in 30% yield with a mol. weight of approx. 4.1 × 103 as estimated by 13C NMR data; the polymer was quant. obtained after 48 h. The obtained polymer was rich in the S-configuration. The structure of the bisoxazoline ligand significantly affected the catalyst activity and stereoselectivity.

Although many compounds look similar to this compound(132098-59-0)Computed Properties of C19H18N2O2, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane(SMILESS: C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1,cas:132098-59-0) is researched.Recommanded Product: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole. The article 《A study on chiral organocalcium complexes: attempts in enantioselective catalytic hydrosilylation and intramolecular hydroamination of alkenes》 in relation to this compound, is published in Zeitschrift fuer Naturforschung, B: Chemical Sciences. Let’s take a look at the latest research on this compound (cas:132098-59-0).

The chiral β-diketimine ligand [(S)-Ph(Me)CH-N:C(Me)]CH2 was prepared by condensation of acetylacetone with the com. available chiral building block (S)-Ph(Me)CH-NH2. Reaction of bis(o-Me2N-α-Me3Si-benzyl)calcium with this β-diketimine led to double deprotonation. Reaction of bis(o-Me2N-α-Me3Si-benzyl)calcium with the com. available chiral bis-oxazoline (S)-Ph-BOX gave diastereopure [(S)-Ph-BOX](o-Me2N-α-Me3Si-benzyl)calcium which in solution slowly decomposed with formation of o-Me2N-α-Me3Si-toluene. The corresponding amide complex [(S)-Ph-BOX]CaN(SiMe3)2·(THF)2 is stable and the crystal structure has been determined In solution, this heteroleptic amide is in Schlenk equilibrium with the homoleptic species [(S)-Ph-BOX]2Ca and Ca[N(SiMe3)2]2·(THF)2. This Schlenk equilibrium can be steered to the heteroleptic side. Use of the enantiopure calcium amide catalyst for the hydrosilylation of styrene with PhSiH3 or in the intramol. hydroamination of aminoalkenes gave good product yields, but only small ee-values were observed (5-10%). From stoichiometric reactions of the catalyst with the substrates it is concluded that the “”true”” catalytically active species is mainly present as a homoleptic calcium complex, which explains the poor enantioselectivities.

Although many compounds look similar to this compound(132098-59-0)Name: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Enantioselective conversion of aldehydes to cyanohydrins by a catalytic system with separate chiral binding sites for aldehyde and cyanide components.Electric Literature of C19H18N2O2.

A new enantioselective method for the synthesis of chiral cyanohydrins from aldehydes and trimethylsilyl cyanide is described which uses a pair of synergistic chiral reagents, one to activate the aldehyde and the other to provide an equivalent of chiral cyanide ion. Thus, cyclohexanecarboxaldehyde was treated with Me3SiCN in the presence of chiral bisoxazoline I and the Mg complex II in EtCN-CH2Cl2 to give 94% the (S)-cyanohydrin silyl ether III in 94% ee.

Although many compounds look similar to this compound(132098-59-0)Electric Literature of C19H18N2O2, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Computed Properties of C19H18N2O2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Ni(II)-catalyzed asymmetric alkenylations of ketimines. Author is Quan, Mao; Wang, Xiaoxiao; Wu, Liang; Gridnev, Ilya D.; Yang, Guoqiang; Zhang, Wanbin.

Ni(II)-catalyzed asym. alkenylation of cyclic ketimines I [R = Me, cyclopropyl, CO2Me, etc.; R1 = H, 8-Me, 7-Cl, etc.; n = 0, 1] with R2CH=CHB(OH)2 (R2 = n-Pr, cyclohexyl, Ph, etc.) for the preparation of chiral allylic amines II was reported. The method well tolerated a variety of ketimines and alkenylboronic acids R2CH=CHB(OH)2 and afforded the desired products in good yields (up to 99%) and enantioselectivities (up to >99% ee). A Ni(II)-catalyzed asym. cascade alkenylation/ring-expansion reaction of alkenyl cyclic ketimines was also developed to yield a series of seven-membered chiral sulfonamides III [R3 = t-Bu, i-Pr, cyclohexyl.; R4 = C6H5, 3-FC6H4, etc.] with good yields and enantioselectivities under mild reaction conditions. This reaction was also an efficient method for the preparation of trisubstituted conjugated dienes. Mechanistic studies showed that the alkenylation was the enantioselectivity-determining step, while the ring expansion step was a stereospecific process. The site-selectivity of the ring rearrangement expansion could be controlled by the formation of a large p-conjugated system or by steric interactions. Transformations of products for both types of reactions were also conducted to show the potential applications of this methodologies.

Although many compounds look similar to this compound(132098-59-0)Computed Properties of C19H18N2O2, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Improvement of ligand economy controlled by polymer morphology: The case of polymer-Supported bis(oxazoline) catalysts, the main research direction is enantioselective polymer supported bisoxazoline catalyst preparation morphol; organic reaction enantioselective polymer Supported bisoxazoline catalyst.Quality Control of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane.

A functionalized chiral bis(oxazoline) is used as a chiral monomer in polymerization reactions leading to homo- and copolymers of different morphol. Polymers with a high content of chiral monomer lead to enantioselectivities that are higher than those obtained with the soluble ligand, but the chiral ligand is not used in an optimal way. A hyperbranched polymer, obtained by using a hexavinyl dendrimer as the cross-linker, leads to the same enantioselectivities with a more efficient use of the chiral ligand.

Although many compounds look similar to this compound(132098-59-0)Quality Control of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Han, Bowen; Li, Yanjun; Yu, Ying; Gong, Lei published an article about the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0,SMILESS:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1 ).Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:132098-59-0) through the article.

An effective strategy by means of single-electron-transfer (SET) initiated formation of radicals and photoactive intermediates to address the long-standing problems. Through elaborate selection of well-matched reaction partners, the chiral bisoxazoline copper catalyst was engaged in the SET process, photoredox catalysis, Lewis acid activation and asym. induction. Accordingly, a highly enantioselective photocatalytic α-aminoalkylation of acyclic imine derivatives was accessed. This strategy sheds light on how to make use of diverse functions of a single transition metal catalyst in one reaction, and offered an economic and simplified approach to construction of highly valuable chiral vicinal diamines I [R1 = H, Me, Et, i-Pr, Ph; R2 = H, 4-Me, 4-Br, etc.; Ar = Ph, 2-MeC6H4, 1-naphthyl, etc.].

Although many compounds look similar to this compound(132098-59-0)Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Single Enantiomer, Chiral Donor-Acceptor Metal Complexes from Bisoxazoline Pseudoracemates, published in 2006-06-22, which mentions a compound: 132098-59-0, Name is Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, Molecular C19H18N2O2, Related Products of 132098-59-0.

Single enantiomer, chiral donor-acceptor metal complexes (I) were synthesized via the self-discriminating zinc(II) complexation of a pseudoracemic mixture of donor/acceptor-substituted bisoxazoline derivatives

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles