Category: 132098-59-0

Hong, Sukwon; Tian, Shun; Metz, Matthew V.; Marks, Tobin J. published an article about the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0,SMILESS:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1 ).Electric Literature of C19H18N2O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:132098-59-0) through the article.

C2-sym. bis(oxazolinato)lanthanide complexes of the type [(4R,5S)-Ph2Box]La[N(TMS)2]2, [(4S,5R)-Ar2Box]La[N(TMS)2]2, and [(4S)-Ph-5,5-Me2Box]La[N(TMS)2]2 (Box = 2,2′-bis(2-oxazoline)methylenyl; Ar = 4-tert-butylphenyl, 1-naphthyl; TMS = SiMe3) serve as precatalysts for the efficient enantioselective intramol. hydroamination/cyclization of aminoalkenes and aminodienes. These new catalyst systems are conveniently generated in situ from the known metal precursors Ln[N(TMS)2]3 or Ln[CH(TMS)2]3 (Ln = La, Nd, Sm, Y, Lu) and 1.2 equiv of com. available or readily prepared bis(oxazoline) ligands such as (4R,5S)-Ph2BoxH, (4S,5R)-Ar2BoxH, and (4S)-Ph-5,5-Me2BoxH. The X-ray crystal structure of [(4S)-tBuBox]Lu[CH(TMS)2]2 provides insight into the structure of the in situ generated precatalyst species. Lanthanides having the largest ionic radii exhibit the highest turnover frequencies as well as enantioselectivities. Reaction rates maximize near 1:1 BoxH:Ln ratio (ligand acceleration); however, increasing the ratio to 2:1 BoxH:Ln decreases the reaction rate, while affording enantiomeric excesses similar to the 1:1 BoxH:Ln case. A screening study of bis(oxazoline) ligands reveals that aryl stereodirecting groups at the oxazoline ring 4 position and addnl. substitution (geminal di-Me or aryl) at the 5 position are crucial for high turnover frequencies and good enantioselectivities. The optimized precatalyst, in situ generated [(4R,5S)-Ph2Box]La[N(TMS)2]2, exhibits good rates and enantioselectivities, comparable to or greater than those achieved with chiral C1-sym. organolanthanocene catalysts, even for poorly responsive substrates (up to 67% ee at 23 °C). Kinetic studies reveal that hydroamination rates are zero order in [amine substrate] and first order in [catalyst], implicating the same general mechanism for organolanthanide-catalyzed hydroamination/cyclizations (intramol. turnover-limiting olefin insertion followed by the rapid protonolysis of an Ln-C bond by amine substrate) and implying that the active catalytic species is monomeric.

From this literature《C2-Symmetric Bis(oxazolinato)lanthanide Catalysts for Enantioselective Intramolecular Hydroamination/Cyclization》,we know some information about this compound(132098-59-0)Electric Literature of C19H18N2O2, but this is not all information, there are many literatures related to this compound(132098-59-0).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane(SMILESS: C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1,cas:132098-59-0) is researched.Product Details of 676-96-0. The article 《Catalytic asymmetric heterogeneous aziridination of styrene using CuHY: effect of nitrene donor on enantioselectivity》 in relation to this compound, is published in Journal of the Chemical Society, Perkin Transactions 2. Let’s take a look at the latest research on this compound (cas:132098-59-0).

The copper-catalyzed aziridination of styrene with copper-exchanged zeolite Y (CuHY) and copper(II) triflate as catalysts is described in detail. Two nitrene donors, [N-(p-tolylsulfonyl)imino]phenyliodinane (PhI:NTs) and [N-(p-nitrophenylsulfonyl)imino]phenyliodinane (PhI:NNs) are compared. Modification of the CuHY catalyst with nonracemic bis(oxazolines) affords enantioselective heterogeneous catalysts; a range of chiral bis(oxazolines) were studied. The ratio of nitrene donor to styrene is shown to be an important factor controlling both the yield and ee of aziridine formed. The best results are obtained with PhI:NNs; ee, ≥ 90%, together with high yields (≥ 85%), can readily be achieved with this nitrene donor using acetonitrile as solvent. Addition of the nitrene donor over a period of time, rather than all at the start of the reaction, is shown to enhance the yield of the aziridine but to decrease the enantiomeric excess of the aziridine for both homogeneous and heterogeneous catalysts. Experiments in which the breakdown products of the nitrene donor, iodobenzene and the corresponding sulfonamide, are added at the start of the reaction show that a complex interplay exists at the copper active site between the reactants, products, chiral modifier and the solvent. The heterogeneous catalyst, CuHY, is found to give enhanced enantioselection for a range of bis(oxazolines) compared to the homogeneous catalyst; the effect is due to the confinement of the catalyst within the micropores of the zeolite.

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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Le Roux, Erwan; Merle, Nicolas; Toernroos, Karl W. published an article about the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0,SMILESS:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1 ).Application of 132098-59-0. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:132098-59-0) through the article.

A series of zinc(II) alkyl complexes I (1a-c, M = ZnEt) stabilized by the C2-chiral bis(oxazolinato) (HR1,R2BOX) ligands [a, R1 = (4S)-tBu, R2 = H; b, R1 = (4S)-Ph, R2 = H; c, R1 = (4R)-Ph, R2 = (5S)-Ph], has been prepared by metalation of the methylenebis(oxazoline) proligands with diethylzinc and structurally characterized. In an excess of HR1,R2BOX proligands, the homoleptic four-coordinate bis-BOX complexes (2a,b, shown as I2, M = 1/2Zn) were isolated; the crowded ligand c did not give bis-BOX complex. The BOC-ethylzinc complexes 1a-c react readily with protic reagents such as acetic acid (HOAc) and methanol (MeOH). From reaction of 1a,b the homoleptic complexes 2a,b were isolated, resulting from redistribution and formation of Zn acetate, whereas the 1c gave acetato-bridged dimer [3c’, shown as I2, R1 = R2 = Ph, M = (μ-AcO)Zn]. From reaction of 1b with MeOH, the methoxy-bridged complex [4b’, shown as I2, R1 = Ph, R2 = H, M = (μ-MeO)Zn] was obtained, via a three-coordinate complex (4c, shown as I, R1 = Ph, R2 = H, M = ZnOMe). The reaction of acetylacetone (acacH) with compounds 1a-c leads straightforwardly to the more stable four-coordinate compounds I [5a-c, M = Zn(acac)]. The potential of these compounds as initiators for the copolymerization of epoxides with CO2 was investigated.

There is still a lot of research devoted to this compound(SMILES：C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Application of 132098-59-0, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane(SMILESS: C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1,cas:132098-59-0) is researched.Name: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole. The article 《Chiral Bis(oxazoline) Ligands as C2-Symmetric Chiral Auxiliaries for the Synthesis of Enantiomerically Pure Bis-Cyclometalated Rhodium(III) Complexes》 in relation to this compound, is published in Organometallics. Let’s take a look at the latest research on this compound (cas:132098-59-0).

The synthesis of enantiomerically pure bis-cyclometalated rhodium(III) complexes using chiral bis(oxazoline) ligands as C2-sym. chiral auxiliaries is described. Bis(oxazolines) are versatile chiral ligands for asym. catalysis but have not been applied to the resolution of racemic mixtures of transition-metal complexes. Due to their C2 symmetry, chiral bis(oxazolines) are particularly useful for the synthesis of nonracemic transition-metal complexes with lower symmetry, and this is demonstrated with the synthesis of an enantiomerically pure rhodium(III) complex containing two different cyclometalated ligands.

There is still a lot of research devoted to this compound(SMILES：C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Formula: C19H18N2O2, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0 ) is researched.Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane.Dakovic, Senka; Liscic-Tumir, Lidija; Kirin, Srecko I.; Vinkovic, Vladimir; Raza, Zlata; Suste, Andreja; Sunjic, Vitomir published the article 《Enantioselectivity in cyclopropanation catalyzed by Cu(I) complexes increased by π stacking of two monodentate oxazoline ligands》 about this compound( cas:132098-59-0 ) in Journal of Molecular Catalysis A: Chemical. Keywords: enantioselective cyclopropanation copper oxazoline; pi stacking stereoselective cyclopropanation copper oxazoline. Let’s learn more about this compound (cas:132098-59-0).

Cu(I) complexes of monodentate ligands (R)-2,4-diphenyloxazoline and (R)-2-isopropyl-4-phenyloxazoline exhibited a significant increase of enantioselectivity in cyclopropanation of styrene vs. other oxazolidine ligands, thus indicating participation in the catalytic cycles of conformationally distinguishable 2:1 (ligand/Cu) complexes, stabilized by π stacking of Ph groups on the chiral center.

There is still a lot of research devoted to this compound(SMILES：C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Schulz, Manfred; Kluge, Ralph; Gelalcha, Feyissa Gadissa published an article about the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0,SMILESS:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1 ).HPLC of Formula: 132098-59-0. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:132098-59-0) through the article.

Cyclohexene, cyclopentene, α-angelica lactone, allylbenzene, and 2-phenylbutane were converted to optically active allylic and benzylic tert-Bu peroxides in good yields and ee values of 4-20% in the title systems. Oxidations of 1-substituted cyclohexenes led to mixtures of regioisomeric peroxides with different regio- and enantioselectivities, depending on the 1-substituent and the ligand used. The highest ee values (up to 84%) were observed for (S)-3-(tert-butylperoxy)-1-methylcyclohexene.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Application of 132098-59-0. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Enantioselective Free Radical Carbon-Carbon Bond Forming Reactions: Chiral Lewis Acid Promoted Acyclic Additions. Author is Wu, Jason Hongliu; Radinov, Rumen; Porter, Ned A..

The reaction of the acrylamide derived from the parent achiral oxazolidinone, I, with alkyl iodides (R-I), and allyltributylstannane has been investigated. The free radical reaction is promoted by Lewis acids such that clean conversion to the (1:1:1, R:I:allyl) adduct II, takes place in low temperature reactions initiated with triethylborane. In the presence of zinc triflate and chiral bis(oxazolines), III, derived from amino alcs., excellent yields of the (1:1:1) adduct are formed. Furthermore, this adduct is formed with good to excellent enantioselectivity. A model is suggested involving an intermediate complex of the radical, zinc ion, and the chiral ligand. The product is hydrolyzed and methylated to give the corresponding Me ester and the configuration of this ester is determined to be S if the bis(oxazoline) has the S,S configuration.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 132098-59-0, is researched, SMILESS is C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1, Molecular C19H18N2O2Journal, Polymer Preprints (American Chemical Society, Division of Polymer Chemistry) called Heterogeneous catalysts for asymmetric hydrogenation of enamides using molecular imprinting technology, Author is Liu, Xiao-Chuan; Lee, Justine; Bernard, Steven, the main research direction is heterogeneous catalyst asym hydrogenation enamides mol imprinting.Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane.

We have successfully synthesized a new class of heterogeneous catalysts for asym. hydrogenation of enamides combining transition metal catalysis and mol. imprinting technol. These new catalysts are MIPs made from rhodium (I) and copper (II) complexes with the bis(oxazoline) chiral ligands. One of the Rh-MIPs showed 87% ee toward L- enantiomeric product while the Cu-MIP showed 82% ee toward D- enantiomeric product. Both MIPs are easy to sep. and reusable.

If you want to learn more about this compound(Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane)Reference of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(132098-59-0).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 132098-59-0, is researched, Molecular C19H18N2O2, about Bifunctional Photocatalysts for Enantioselective Aerobic Oxidation of β-Ketoesters, the main research direction is ketoester oxygen visible light enantioselective aerobic oxidation nickel bisoxazoline; chiral hydroxy ketoester preparation mol crystal structure; bisoxazoline ligand grafted photosensitizer bifunctional enantioselective aerobic oxidation photocatalyst.Related Products of 132098-59-0.

A novel visible-light-responsive chiral ligand has been developed by grafting a triplet state photosensitizer to chiral bisoxazoline ligands. Complexation of this ligand with Ni(acac)2 results in a powerful catalyst for the asym. oxidation reaction of β-ketoesters, which uses oxygen or air as the green oxidant and visible light or sunlight as the ideal driving force. Using this protocol, products containing the α-hydroxy-β-dicarbonyl motif, e.g., I, are produced in high yields and with excellent enantiopurities.

If you want to learn more about this compound(Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane)Related Products of 132098-59-0, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(132098-59-0).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C19H18N2O2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about A conformational toolbox of oxazoline ligands. Author is Davies, Ian W.; Gerena, Linda; Cai, Dongwei; Larsen, Robert D.; Verhoeven, Thomas R.; Reider, Paul J..

A toolbox of bis(oxazoline) and pyridinebis(oxazoline) ligands I-III (X = CMe2, indan-2,2-diyl, pyridine-2,6-diyl) has been used to probe conformational effects in Cu(II)-catalyzed Diels-Alder and Ru(II)-catalyzed cyclopropanation reactions.

Here is a brief introduction to this compound(132098-59-0)COA of Formula: C19H18N2O2, if you want to know about other compounds related to this compound(132098-59-0), you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles