In an article, author is Singh, Gurjaspreet, once mentioned the application of 16830-15-2, COA of Formula: https://www.ambeed.com/products/16830-15-2.html, Name is Asiaticoside, molecular formula is C48H78O19, molecular weight is 959.1215, MDL number is MFCD06642601, category is indole-building-block. Now introduce a scientific discovery about this category.
A triazole tethered chemo sensor molecules with the capability of sensing cations have been synthesized by coupling two sensor based alkynyl indole schiff base unit to azide. The hybrid networks were able to donate electron via azomethine linkage, traizole ring and indole motif to bind copper and nickel effectively. Such indole based hybrids would have potential applications in biological systems. Indole traizoles (In-Tz) were synthesized under microwave irradiation with auto generated pressure (at 60 degrees C) and characterized by 1H NMR, 13C NMR, Mass and FTIR spectroscopy, thin-layer chromatography (TLC) and elemental analyses. The fabricated sensor exhibited higher sensitivity, large-dynamic concentration ranges and long term stability towards In-Tz conjugated copper and nickel complex for selective Cu2+ and Ni2+ sensor. The calibration plot is linear (r(2): 0.9895, r(2): 0.9808) over the large Cu2+ ions and Ni2+ concentration ranges (1.0 mu M). This novel effort has initiated a well-organize way of efficient cationic sensor improvement with triazole for heavy metallic pollutants in environmental and health-care fields in large scales. (C) 2018 Elsevier B.V. All rights reserved.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles