17422-32-1, 5-Chloroindole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
[1238] Preparation of DJ-2 . To a solution of DJ-1 (1 g, 6.60 mmol, 1 eq) in DMF (10 mL) was added KOH (925.27 mg, 16.49 mmol, 2.5 eq) followed by dropwise addition of I2 (1.67 g, 6.60 mmol, 1.33 mL, 1 eq) in DMF (10 mL). The mixture was stirred at 10C. for 2 h to give a red-brown solution. LCMS showed the reaction was completed. The reaction mixture was quenched with H2O (60 mL) and extracted with MBTE (20 mL3). The organic layers were dried over Na2SO4 and concentrated to give the crude product, which was used for next step without further purification., 17422-32-1
17422-32-1 5-Chloroindole 87110, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Patent; Ferro Therapeutics, Inc.; Jiang, Chun; Chen, Ruihong; Pandey, Anjali; Kalita, Biswajit; Duraiswamy, Athisayamani Jeyaraj; (293 pag.)US2019/263802; (2019); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles