Category: 23746-76-1

Li, Qiuyu et al. published their research in Organic Letters in 2022 | CAS: 23746-76-1

5-Chloro-2-phenyl-1H-indole (cas: 23746-76-1) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.COA of Formula: C14H10ClN

Palladium-Catalyzed Asymmetric Dearomative Carbonylation of Indoles was written by Li, Qiuyu;Zhang, Yunchu;Zeng, Yuye;Fan, Yujing;Lin, Aijun;Yao, Hequan. And the article was included in Organic Letters in 2022.COA of Formula: C14H10ClN This article mentions the following:

Herein, authors disclose a strategy for the asym. dearomatization of N-arylacyl indoles via a palladium-catalyzed tandem Heck/carbonylation, leading to an array of indoline-3-carboxylates bearing vicinal C2-aza-quaternary and C3 tertiary stereocenters in high yields and excellent enantio- and diastereoselectivities. This study is an important advance in the field of asym. carbonylation and enantioselective dearomatization reactions. In the experiment, the researchers used many compounds, for example, 5-Chloro-2-phenyl-1H-indole (cas: 23746-76-1COA of Formula: C14H10ClN).

5-Chloro-2-phenyl-1H-indole (cas: 23746-76-1) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. More than 200 indole derivatives have already been marketed as drugs or are under advanced stages of clinical trials.COA of Formula: C14H10ClN

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Extracurricular laboratory:new discovery of 5-Chloro-2-phenyl-1H-indole

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Synthetic Route of 23746-76-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 23746-76-1, Name is 5-Chloro-2-phenyl-1H-indole,introducing its new discovery.

The invention relates to thiophene-imidazopyridine compounds according to formula (I), wherein the substituents and symbols are as defined in the description. The compounds are inhibitors of PIk1

If you’re interested in learning more about 10314-98-4, below is a message from the blog Manager. Synthetic Route of 23746-76-1

Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles