A thermodynamic study on thermochromism of 3-(1,2-dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide was written by Kim, Jae-Uk;Ji, Myoung-Jin;Kim, Jong-Gyu. And the article was included in Journal of the Korean Chemical Society in 2009.Synthetic Route of C29H30N2O2 This article mentions the following:
The thermochromism of 3-(1,2-dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide (DIDMP) is studied by UV-VIS absorption spectroscopy. The DIDMP shows a closed form under solvent and changes to an open form in the presence of acid and the absorption spectra shows the increased intensity as function of the temperature increase. From the absorption spectra, the equilibrium constant between a closed and an open form is obtained and the corresponding enthalpy change was also obtained as function of various solvents. In the experiment, the researchers used many compounds, for example, 3-(4-(Diethylamino)-2-methylphenyl)-3-(1,2-dimethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one (cas: 36499-49-7Synthetic Route of C29H30N2O2).
3-(4-(Diethylamino)-2-methylphenyl)-3-(1,2-dimethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one (cas: 36499-49-7) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Synthetic Route of C29H30N2O2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles