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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 4264-35-1, name is 1-(1H-Indol-2-yl)ethanone, introducing its new discovery. SDS of cas: 4264-35-1

A novel InCl3-mediated one-pot reaction leading to 1-aminocarbazoles is reported. Starting from easily available 2-acetyl-1H-indole, the reaction involves the alkylation of C-3 with a prop-2-yn-1-ol followed by a domino aminobenzannulation reaction in the presence of a secondary amine. The indium salt is most likely involved as catalyst in all three steps of the one-pot reaction. Starting from 2-acetyl-1H-indole and a series of prop-2-yn-1-ols and secondary amines a small library of products has been obtained.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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Compounds having a structure of Formulas A-C are provided. Uses of such compounds as an antibiotic, including both gram-negative and gram-positive micro-organisms, as well as methods of treatment and uses involving such compounds are provided

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C10H9NO. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 4264-35-1

2-Acyl-N-propargylindoles 1 and 2-acyl-3-propargylindoles 5 undergo aminobenzannulation reactions with pyrrolidine in the presence of an appropriate Lewis acid to give 9-aminopyrido[1,2-alpha]indoles 6 and 1-aminocarbazoles 7, respectively. The selection of the appropriate Lewis acid, TiCl4 or GaCl3 for 1 and InCl3 for 5, allows the domino process involving the initial formation of an enamine intermediate, followed by a regioselective 6-exo-dig intramolecular nucleophilic attack of the nucleophilic terminus of the unsaturated system (the beta-carbon of the enamino moiety) to the carbon-carbon triple bond. Moreover, several features concerning the reaction mechanism and the role of both catalysts, in connection with the electronic properties of the reacting alkynes, are reported. Wiley-VCH Verlag GmbH & Co. KGaA.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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Complex cyclic azomethine imines possessing a beta-aminocarbonyl motif can be accessed readily from simple alkenes and hydrazones. This alkene aminocarbonylation approach allows formation of ketone-derived azomethine imines of unprecedented complexity. Since unsymmetrical hydrazones are used, two stereoisomers are formed: the reactivity of chiral derivatives is explored in both intra- and intermolecular systems.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Formula: C10H9NO, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 4264-35-1, Name is 1-(1H-Indol-2-yl)ethanone, molecular formula is C10H9NO. In a Article, authors is Black, David St. C.,once mentioned of 4264-35-1

N-Phenacyl- and N-acetonyl-isatins can be prepared and converted by treatment with sodium hydroxide into 2-acyl indoles and/or 2-acyl indole-3-carboxylic acids.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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(Chemical Equation Presented) An original TiCl4/t-BuNH 2-mediated hydroamination/annulation domino reaction of delta-keto-acetylenes is described. The synthesis of pyrrolo[1,2-a]indole-2- carbaldehydes, starting from 2-carbonyl-1-propargyl-1H-indoles runs under mild reaction conditions, A conceivable mechanism is also discussed. TiCl4 has proved to be an effective multiactivity reagent: catalyst/Lewis acid/water scavenger. Some unpublished 2-carbonyl-1-propargyl-1H-indoles are prepared by means of Suzuki- and Negishi-lype reactions.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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A short synthetic route to 16-demethyleneervitsine (6), based on the nucleophilic addition of 2-acetylindole enolates to N-alkyl-beta-acylpyridinium salts and further acid cyclization of the resulting 1,4-dihydropyridine intermediates, is reported.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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The synthesis of several new heterocyclic structural analogs of the natural antimitotic agent allocolchicine is reported. As a key step an intramolecular Pd-catalyzed C-H arylation reaction was used to close the seven-membered ring fused with two electron-rich aryl fragments. The stereostructure of the target compounds was determined by X-ray crystal analysis. The primary biological assessment of the synthesized compounds was carried out on human lymphoma cells. Several allocolchicinoids were determined to possess antiproliferative and apoptosis-inducing activity in the micromolar concentration range. The synthesis of indole-derived structural analogs of natural antimitotic agent allocolchicine is reported. In a key step, an intramolecular Pd-catalyzed C-H arylation reaction serves to construct the polycyclic ring system, by connecting the two electron-rich arene fragments.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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Three cation-pi cyclization cascades initiated at alkylidene beta-ketoesters bearing pendent alkenes are described. Depending upon the alkene substitution pattern and the reaction conditions employed, it is possible to achieve selective synthesis of the three different types of products, including 1-halo-3-carbomethoxycyclohexanes, spiro-fused tricyclic systems, and [4.3.1] bridged bicyclic ring systems. All three reactions begin with 6-endo addition of an olefin to the alkylidene beta-ketoester electrophile, followed by one of three different cation capture events.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

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The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4264-35-1 is helpful to your research. SDS of cas: 4264-35-1

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 4264-35-1, name is 1-(1H-Indol-2-yl)ethanone, introducing its new discovery. SDS of cas: 4264-35-1

Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester

Methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate acts as an efficient alkylating agent for a variety of five-membered aromatic heterocycles. The aziridines derived from heterocycles that bear an alpha- carbonyl substituent react with TFA to give pyrroloimidazoles; 2,6- dichlorobenzaldehyde is also produced. (C) 2000 Elsevier Science Ltd.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4264-35-1 is helpful to your research. SDS of cas: 4264-35-1

Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles