Let’s face it, organic chemistry can seem difficult to learn, Safety of 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, Especially from a beginner’s point of view. Like 446-72-0, Name is 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, molecular formula is indole-building-block, belongs to indole-building-block compound. In a document, author is Pearson, Stuart E., introducing its new discovery.
Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting materials using several different methods is also described.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles