Electric Literature of 499-44-5, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 499-44-5, Name is Hinokitiol, SMILES is O=C1C(O)=CC(C(C)C)=CC=C1, belongs to indole-building-block compound. In a article, author is Yu, Shuowen, introduce new discover of the category.
By employing a chiral phosphoric acid as a catalyst, enantioselective domino Friedel-Crafts-type reaction of indole-3-butanal with indoles was realized. This transformation allowed for the synthesis of a wide variety of enantioenriched 1-indolyl-tetrahydrocarbazoles with good yields (up to 99%) in moderate enantioselectivities (up to 81% ee).
Electric Literature of 499-44-5, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 499-44-5.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles