Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter.52927-22-7, Name is 6-Hydroxy-2-naphthonitrile, SMILES is C(#N)C2=CC=C1C=C(C=CC1=C2)O, belongs to indole-building-block compound. In a document, author is Yang, Ji, introduce the new discover, Safety of 6-Hydroxy-2-naphthonitrile.
Four new monoterpenoid indole alkaloids (MIAs), scholarisines P-S (1-4), and 14 known MIAs (5-18) were isolated from the leaves of Aistonia scholaris (L) R. Br. (Apocynaceae). Their structures were elucidated by analyzing their HRESIMS data and NMR spectroscopic data. All of the isolated MIAs were evaluated for their Nuclear Factor-kappa B (NF-kappa B) inhibitory activity in HepG2-NF-kappa B-Luc cells. Among them, five compounds (4, 7, 8, 13 and 16) exhibited significant NF-kappa B inhibitory activity.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 52927-22-7 is helpful to your research. Safety of 6-Hydroxy-2-naphthonitrile.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles