Analyzing the synthesis route of 53590-58-2

53590-58-2 (6-Chloro-1H-indol-2-yl)methanol 16115151, aindole-building-block compound, is more and more widely used in various.

53590-58-2, (6-Chloro-1H-indol-2-yl)methanol is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,53590-58-2

To (6-chloro-1H-indol-2-yl)-methanol (37.7 mmol) in THF at 0 C. was added manganese (IV) oxide and the mixture was stirred at room temperature for 16 h. The mixture was filtered over celite and rinsed with THF and EtOAc and evaporated to near dryness. The solid was filtered and washed with cold EtOAc/hex to give 6-chloro-1H-indole-2-carbaldehyde (62%, 2 steps).

53590-58-2 (6-Chloro-1H-indol-2-yl)methanol 16115151, aindole-building-block compound, is more and more widely used in various.

Reference£º
Patent; Wyeth; US2008/9485; (2008); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles