Category: 65417-22-3

Irvine, Robert W.; Summers, John C.; Taylor, Walter C. published an article in 1983, the title of the article was Photochemistry of dimethyl quinoline-3,4-dicarboxylate N-oxides.Safety of Methyl 2-methyl-1H-indole-3-carboxylate And the article contains the following content:

The photochem. rearrangement of di-Me 2-methyl- and 2-aryl-substituted quinoline-3,4-dicarboxylate N-oxides are examined In MeOH or MeOH-CHCl3 the major product was the 1-methyl- or 1-arylquinolin-2(1H)-one in which the substituent at C-2 has migrated to the N atom. The yield of these products was increased in a dark reaction subsequent to the irradiation In MeCN the inital major product was the corresponding 3,1-benzoxazepine; subsequent reactions yielded inter alia indole derivatives The intermediacy of fused oxaziridines or their ring opened isomeric zwittterions is discussed. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Safety of Methyl 2-methyl-1H-indole-3-carboxylate

The Article related to photochem rearrangement mechanism quinolinedicarboxylate oxide, Physical Organic Chemistry: Rearrangements, Including Isomerization and Tautomerization and other aspects.Safety of Methyl 2-methyl-1H-indole-3-carboxylate

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Shi, Yao; Ke, Zhihai; Yeung, Ying-Yeung published an article in 2018, the title of the article was Environmentally benign indole-catalyzed position-selective halogenation of thioarenes and other aromatics.Category: indole-building-block And the article contains the following content:

An environmentally benign protocol for the synthesis of aryl bromides RBr [R = 3,4-di-MeOC6H3, 4-MeSC6H4, 2-Me-thienyl, etc.] was developed via regioselective electrophilic bromination of aromatic compounds Indole-catalyst was suitable for a wide range of substrates including thioarenes. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Category: indole-building-block

The Article related to bromoarene green preparation regioselective, thioether bromination indole organocatalyst, arene bromination indole organocatalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Category: indole-building-block

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Chen, Xiaohong; Zheng, Guangfan; Song, Guoyong; Li, Xingwei published an article in 2018, the title of the article was Rhodium(III)-Catalyzed Synthesis of Cinnolinium Salts from Azobenzenes and Diazo Compounds.Recommanded Product: 65417-22-3 And the article contains the following content:

A Rh(III)-catalyzed C-H activation of azobenzenes in the coupling with diazo compounds has been realized, providing a straightforward strategy to access functionalized cinnolinium triflates, e.g., I in high yields. This protocol features silver free mild reaction conditions and compatibility with diverse functional groups. The coupling proceeds via initial Rh(III)-catalyzed C-H alkylation, followed by zinc triflate-mediated cyclization, where zinc triflate acts as a Lewis acid as well as a triflate source. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Recommanded Product: 65417-22-3

The Article related to cinnolinium salt preparation, azobenzene diazo compound carbon hydrogen activation coupling rhodium catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Pyridazines, Cinnolines, and Phthalazines and other aspects.Recommanded Product: 65417-22-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On September 30, 1993, Guven, Alaattin; Jones, R. Alan published an article.Recommanded Product: Methyl 2-methyl-1H-indole-3-carboxylate The title of the article was Potentially tautomeric 1,2-dihydro-1-oxo-5H-pyridazino[4,5-b]indole and 3,4-dihydro-4-oxo-5H-pyridazino[4,5-b]indole. And the article contained the following:

The potentially tautomeric title compounds I and II were synthesized from Et 2-formylindole-3-carboxylate and hydrazine and from Et 3-formylindole-2-carboxylate and hydrazine, resp., and their tautomeric equilibrium confirmed by their electronic spectra and their acidity functions. Many related compounds were examined for their tautomeric equilibrium between hydroxyl and oxo groups. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Recommanded Product: Methyl 2-methyl-1H-indole-3-carboxylate

The Article related to tautomerism dihydrooxopyridazinoindole, pyridazinoidole dihydrooxo tautomerism, electronic spectra dihydrooxopyridazinoindole, Heterocyclic Compounds (More Than One Hetero Atom): Pyridazines, Cinnolines, and Phthalazines and other aspects.Recommanded Product: Methyl 2-methyl-1H-indole-3-carboxylate

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On February 19, 2016, Qi, Zisong; Yu, Songjie; Li, Xingwei published an article.Reference of Methyl 2-methyl-1H-indole-3-carboxylate The title of the article was Rh(III)-Catalyzed Synthesis of N-Unprotected Indoles from Imidamides and Diazo Ketoesters via C-H Activation and C-C/C-N Bond Cleavage. And the article contained the following:

The synthesis of N-unprotected indoles has been realized via Rh(III)-catalyzed C-H activation/annulation of imidamides with α-diazo β-ketoesters. The reaction occurs with the release of an amide coproduct, which originates from both the imidamide and the diazo as a result of C=N cleavage of the imidamide and C-C(acyl) cleavage of the diazo. A rhodacyclic intermediate has been isolated and a plausible mechanism has been proposed. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Reference of Methyl 2-methyl-1H-indole-3-carboxylate

The Article related to indole preparation, imidamide diazo ketoester cyclization rh catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Reference of Methyl 2-methyl-1H-indole-3-carboxylate

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On April 28, 2010, Guan, Zheng-Hui; Yan, Ze-Yi; Ren, Zhi-Hui; Liu, Xue-Yuan; Liang, Yong-Min published an article.Synthetic Route of 65417-22-3 The title of the article was Preparation of indoles via iron catalyzed direct oxidative coupling. And the article contained the following:

Iron-catalyzed aryl C-H and vinyl C-H bonds activation to give valuable substituted indole products, e.g. I, from 3-(phenylamino)but-2-enoates, e.g. II, was reported. The reaction shows high functional group tolerance. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Synthetic Route of 65417-22-3

The Article related to indole preparation, phenylaminobutenoate oxidative coupling iron catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Synthetic Route of 65417-22-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On March 15, 2011, Ali, Ashif Md.; Punniyamurthy, Tharmalingam published an article.Safety of Methyl 2-methyl-1H-indole-3-carboxylate The title of the article was Domino ligand-free copper-catalyzed synthesis of polysubstituted indoles. And the article contained the following:

The synthesis of polysubstituted indoles is described by the domino reaction of 2-haloanilines and 1,3-dicarbonyl compounds, 1,3-diketones, β-keto esters and β-keto amides, using copper catalysis under ligand-free conditions. The protocol provides a simple, general and atom economical process for the synthesis of substituted indoles at moderate temperature The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Safety of Methyl 2-methyl-1H-indole-3-carboxylate

The Article related to indole preparation, haloaniline dicarbonyl compound cyclocondensation copper, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of Methyl 2-methyl-1H-indole-3-carboxylate

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On April 28, 2010, Guan, Zheng-Hui; Yan, Ze-Yi; Ren, Zhi-Hui; Liu, Xue-Yuan; Liang, Yong-Min published an article.Synthetic Route of 65417-22-3 The title of the article was Preparation of indoles via iron catalyzed direct oxidative coupling. And the article contained the following:

Iron-catalyzed aryl C-H and vinyl C-H bonds activation to give valuable substituted indole products, e.g. I, from 3-(phenylamino)but-2-enoates, e.g. II, was reported. The reaction shows high functional group tolerance. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Synthetic Route of 65417-22-3

The Article related to indole preparation, phenylaminobutenoate oxidative coupling iron catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Synthetic Route of 65417-22-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On March 15, 2011, Ali, Ashif Md.; Punniyamurthy, Tharmalingam published an article.Safety of Methyl 2-methyl-1H-indole-3-carboxylate The title of the article was Domino ligand-free copper-catalyzed synthesis of polysubstituted indoles. And the article contained the following:

The synthesis of polysubstituted indoles is described by the domino reaction of 2-haloanilines and 1,3-dicarbonyl compounds, 1,3-diketones, β-keto esters and β-keto amides, using copper catalysis under ligand-free conditions. The protocol provides a simple, general and atom economical process for the synthesis of substituted indoles at moderate temperature The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).Safety of Methyl 2-methyl-1H-indole-3-carboxylate

The Article related to indole preparation, haloaniline dicarbonyl compound cyclocondensation copper, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of Methyl 2-methyl-1H-indole-3-carboxylate

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

On December 18, 2012, Bunescu, Ala; Wang, Qian; Zhu, Jieping published an article.SDS of cas: 65417-22-3 The title of the article was Synthesis of indoles by copper-catalyzed heteroannulation of o-aminophenylboronic acid pinacol esters with β-keto esters. And the article contained the following:

Copper-catalyzed coupling of o-aminophenylboronic acid pinacol esters with β-keto esters afforded, under mild base-free oxidative conditions, 2,3-disubstituted indoles featuring a key Chan-Lam-type carbon-carbon bond-forming reaction. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).SDS of cas: 65417-22-3

The Article related to indole preparation, aminophenylboronic acid pinacol ester keto ester copper catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.SDS of cas: 65417-22-3

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles