6855-64-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6855-64-7,2-Phenyl-1H-indol-5-amine,as a common compound, the synthetic route is as follows.
Example 5 Compound 5 N-(2-phenyl-1H-indol-5-yl)acetamidine Prepared in a manner similar to that of Example 1. Yield: (63percent); Elem. anal. C16H15N3 M.W.: 249.31; theory C, 77.08; H, 6.06; N, 16.85. found C, 76.97; H, 6.29; N, 16.85. IR (KBr): 3434, 3024, 1634, 1597 cm-1; 1H-NMR (d6-DMSO) 7.8-6.3 (m, 9H); 1.8 (s, 3H).; Example 7 Compound 5 As an alternative to the method described in Example 5, this product may be prepared as reported below: N-(2-phenyl-1H-indol-5-yl)acetamidine Prepared in a manner similar to that of Example 5. Yield: 60percent; Elem. anal. C16H15N3; theory C, 77.08; H, 6.06; N, 16.85. found C, 77.17; H, 5.89; N, 16.68. IR (KBr): 3434, 3024, 1634, 1597 cm-1; 1H-NMR (d6-DMSO) 7.8-6.3 (m, 9H); 1.8 (s, 3H).
The synthetic route of 6855-64-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; ROTTAPHARM SPA; US2005/197331; (2005); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles