Category: 7147-14-0

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Quality Control of: 5-Nitro-1H-indole-3-carbonitrile, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 7147-14-0, Name is 5-Nitro-1H-indole-3-carbonitrile, molecular formula is C9H5N3O2. In a Patent, authors is ，once mentioned of 7147-14-0

The invention belongs to the technical field of medicines, and particularly relates to 1 – substituted – 3 3-substituted amide – 111H-indole compound as well as a preparation method and application, for 1 – substitution – 3 3-substituted amide: 111H-indole type compound as shown in the following I. The pharmacological research shows, the compound shows good effect, in the in vitro xanthine oxidase inhibition activity test, and no obvious toxic and side effect, provides 1 – substituted – 3 3-substituted amide – 111H-indole compound, the preparation method is simple and feasible, yield is higher, and large-scale production, is easy. (by machine translation)

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Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Synthetic Route of 7147-14-0, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.7147-14-0, Name is 5-Nitro-1H-indole-3-carbonitrile, molecular formula is C9H5N3O2. In a article£¬once mentioned of 7147-14-0

Synthesis and in-vitro anticancer activity of 3,5-bis(indolyl)-1,2,4- thiadiazoles

A series of 3,5-bis(indolyl)-1,2,4-thiadiazoles were synthesized and evaluated for their cytotoxicity against selected human cancer cell lines. The reaction of indole-3-thiocarboxamide 3 with iodobenzene diacetate underwent oxidative dimerization to give 3,5-bis(indolyl)-1,2,4-thiadiazoles 4a-n. Among the synthesized bis(indoly)-1,2,4-thiadiazoles, the compound 4h with 4-chlorobenzyl and methoxy substituents showed the most potent activity.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 7147-14-0, and how the biochemistry of the body works.Synthetic Route of 7147-14-0

Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles