Category: 76-60-8

Kanchana, Subramanian; Vijayalakshmi, Radhakrishnan published an article about the compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide( cas:76-60-8,SMILESS:CC1=C(Br)C(O)=C(Br)C=C1C2(C3=CC(Br)=C(O)C(Br)=C3C)C4=CC=CC=C4S(O2)(=O)=O ).Name: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:76-60-8) through the article.

Photocatalysis mediated by metal nanoparticles is emerging as an effective method for the removal of hazardous dye pollutants in natural aquatic bodies. Nanoparticles of Cu, Ni, and Ag were synthesized by chem. methods using PEG and PVP polymers as capping agents. Exptl. photocatalysis was carried out in a single pot batch reactor using metal nanoparticle catalysts for the degradation of crystal violet (CV), bromocresol green (BCG), and methylene blue (MB) in an aqueous solution in the presence of NaBH4 reductant independently under solar and UV irradiations at 25°C. Metal nanoparticles caused the removal of BCG and CV in 90-120 min and MB in 30-60 min. A linear relationship between the irradiation time and the absorbance was recorded and the kinetic plots exhibited pseudo-first-order kinetic. The trend of dye degradation among the nanoparticles based on the catalytic efficiency (φc) and rate coefficient (k) values was Cu>Ag>Ni. Mineralization experiments indicated 94, 91, and 90% of the TOC removal ratio (R) resp. for CV, MB, and BCG dyes. Nanoparticles stabilized using PEG demonstrated better catalytic efficiency than those with PVP. Solar irradiation showed a superior augmenting effect on the nanoparticle catalysts than the UV irradiation The electron-hole pair mediated reduction mechanism was proposed as a basis for dyes photocatalytic degradation

When you point to this article, it is believed that you are also very interested in this compound(76-60-8)Name: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide and due to space limitations, I can only present the most important information.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide( cas:76-60-8 ) is researched.Synthetic Route of C21H14Br4O5S.Erturk, Suheyl; Yilmaz, Muge Sari; Piskin, Sabriye published the article 《Potential low-cost carbon-based adsorbent from gold mine tailings for anionic dye removal》 about this compound( cas:76-60-8 ) in Water Science & Technology. Keywords: carbon gold mine tailing adsorbent anionic dye removal potential. Let’s learn more about this compound (cas:76-60-8).

In this study, a mesoporous carbon (CMK-3) was successfully synthesized using mesoporous silica (SBA-15) prepared from gold mine tailings (sample CGMT) for removal of anionic dye from aqueous solution For comparison, CMK-3 was prepared by the same method from pure silica (sample CT), and the other CMK-3 sample was prepared by a one-pot route mixing with Pluronic P123 (sample CP). The effect of the carbonization time on the synthesis of all CMK-3 samples was investigated, and the samples were characterized by X-ray diffraction and N2 adsorption-desorption. The sample with the highest surface area was chosen as an adsorbent, for each CMK-3 obtained from different methods. Batch adsorption experiments were studied to determine the influence of pH, contact time, and initial dye concentration The adsorption kinetics obeyed the pseudo-second-order model. All carbon-based adsorbents were observed to be quite effective for the removal of dye with adsorption percentage in the order of CP > CT > CGMT. The maximum adsorption capacities were 188.99 and 204.57 mg·g-1 for CT and CGMT, resp. The comparative results of all carbon-based adsorbents show that CGMT can be applied as a low-cost alternative to CT for dye removal.

As far as I know, this compound(76-60-8)Synthetic Route of C21H14Br4O5S can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 76-60-8, is researched, Molecular C21H14Br4O5S, about Phospholipase-A2 receptor antibody, 24 hours proteinuria, and serum albumin as indicators of cyclophosphamide efficacy in idiopathic membranous nephropathy, the main research direction is cyclophosphamide renoprotectant idiopathic membranous nephropathy; 24h proteinuria; Idiopathic Membranous Nephropathy; PLA2R-Ab; cyclophosphamide; prediction; remission.SDS of cas: 76-60-8.

Background : We aimed to evaluate cyclophosphamide efficacy in the treatment of idiopathic membranous nephropathy (IMN) and explore the efficacy of phospholipase-A2 receptor antibody (PLA2R-Ab), 24 h proteinuria, and serum albumin in predicting 6- and 12-mo treatment effects. Methods : A retrospective anal. was performed on 135 patients with IMN who followed up after treatment. The observation points were before, and after 3, 6, and 12 mo of treatment. We collected clin. indicator data at each observation point and measured PLA2R-Ab levels before and after 3-mo treatment. Results : The remission rates at 3, 6, and 12 mo of cyclophosphamide therapy for patients with IMN were 41.4, 74.8, and 76.1%, resp. Patients in whom PLA2R-Ab turned neg. within 3 mo had high remission rates at 3, 6, and 12 mo after treatment (P < .05). PLA2R-Ab change at 3 mo had a strong correlation with 24 h proteinuria change at 6 mo. The change in albumin concentration before and after 3-mo treatment was an independent variable related to remission rate at 6 mo, and 24 h proteinuria change before and after 6-mo treatment was an independent variable related to remission rate at 12 mo after treatment. Conclusion : Cyclophosphamide showed good efficacy at 3, 6, and 12 mo for patients with IMN. Serum albumin change and PLA2R-Ab change at 3 mo can be used as indicators to predict remission at 6 mo, resp. Moreover, 24 h proteinuria change at 6 mo can predict remission at 12 mo. As far as I know, this compound(76-60-8)SDS of cas: 76-60-8 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide( cas:76-60-8 ) is researched.Product Details of 76-60-8.Suckey, Melissa M.; Benza, Donald W.; DesJardins, John D.; Anker, Jeffrey N. published the article 《Upconversion spectral rulers for transcutaneous displacement measurements》 about this compound( cas:76-60-8 ) in Sensors. Keywords: spectral ruler autofluorescence optical encoder scattering implanted medical device; X-ray excited optical luminescence; autofluorescence; fluorescence; implanted medical device; optical encoder; optical scattering; sensing through tissue; spectral ruler. Let’s learn more about this compound (cas:76-60-8).

We describe a method to measure micron to millimeter displacement through tissue using an upconversion spectral ruler. Measuring stiffness (displacement under load) in muscles, bones, ligaments, and tendons is important for studying and monitoring healing of injuries. Optical displacement measurements are useful because they are sensitive and noninvasive. Optical measurements through tissue must use spectral rather than imaging approaches because optical scattering in the tissue blurs the image with a point spread function typically around the depth of the tissue. Addnl., the optical measurement should have low background and minimal intensity dependence. Previously, we demonstrated a spectral encoder using either X-ray luminescence or fluorescence, but the X-ray luminescence required an expensive X-ray source and used ionizing radiation, while the fluorescence sensor suffered from interference from autofluorescence. Here, we used upconversion, which can be provided with a simple fiber-coupled spectrometer with essentially autofluorescence-free signals. The upconversion phosphors provide a low background signal, and the use of closely spaced spectral peaks minimizes spectral distortion from the tissue. The small displacement noise level (precision) through tissue was 2μm when using a microscope-coupled spectrometer to collect light. We also showed proof of principle for measuring strain on a tendon mimic. The approach provides a simple method to study biomechanics using implantable sensors.

As far as I know, this compound(76-60-8)Product Details of 76-60-8 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide(SMILESS: CC1=C(Br)C(O)=C(Br)C=C1C2(C3=CC(Br)=C(O)C(Br)=C3C)C4=CC=CC=C4S(O2)(=O)=O,cas:76-60-8) is researched.Formula: C44H69NP2. The article 《[Comparison of three albumin assay methods: a need for standardization within a healthcare area].》 in relation to this compound, is published in Annales de biologie clinique. Let’s take a look at the latest research on this compound (cas:76-60-8).

Albumin is a main biomarker of denutrition severity. Since 2019, the French National Authority of Health (HAS) recommends an immunologic technique as a reference for measuring albuminemia. In a context of partial recovery by the laboratory of GHBS (using colorimetric method with bromcresol purple) of the biological activity of the dialysis center, until then carried out by the Ouest biology – Biolor laboratory (using colorimetric method with bromcresol green) and in order to standardize practices in the healthcare sector, we compared 3 albumin assay techniques: immunoturbidimetric (Diagam®), BCG (Siemens®), BCP (Siemens®) on Siemens Atellica PLCs. The albumin level of 183 patient samples was measured. We show an overestimation of the dosage by the BCG (+ 5.46 g/L compared to IT) and an interference related to the inflammatory state of the patient during the dosage with this technique, as well as an underestimation of the dosage by the BCP (- 0.91 g/L relative to the IT), increased in patients with renal injury. This biological difference is added to a discrepancy in clinical conclusions. A change in dosing technique from BCG to BCP may impact the biological follow-up of patients and the PMSI score (mean difference of – 6.67 g/L between BCG and BCP while the classification of the severity of denutrition uses thresholds set in steps of 5 g/L). This variability of results should be taken into account by the clinicians and constitutes an argument in favor of the standardization of laboratories around a reference technique.

This literature about this compound(76-60-8)Category: indole-building-blockhas given us a lot of inspiration, and I hope that the research on this compound(3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide( cas:76-60-8 ) is researched.Application of 76-60-8.Stojkoski, Viktor; Kert, Mateja published the article 《Design of pH responsive textile as a sensor material for acid rain》 about this compound( cas:76-60-8 ) in Polymers (Basel, Switzerland). Keywords: pH sensitive dye rainwater acid rain sensor air pollution; acid rain; bromocresol green; pH sensitive dyes; polyamide 6; water and oil repellency. Let’s learn more about this compound (cas:76-60-8).

The chem. composition of rainwater can serve as an indicator of the excess of acidifying air pollutants. The pH value of rainwater in the presence of sulfur dioxide and nitrogen oxides, the precursors of acid rain, falls below pH 5.6, which is the limit value for acid rain. In this research, the tailoring of halochromic textile was examined for the design of a functional textile that can serve as a sensor and inform the wearer about the presence of pollutants in the air by means of an immediate color change. For this purpose, a polyamide 6 fabric was dyed with the pH-sensitive Bromocresol green dye, which causes a color change below pH 3.6 (yellow) and above pH 5.4 (blue). In addition, the dyed polyamide 6 fabric was treated with a water and oil repellent finish. Color and color change before and after immersion of unfinished and finished dyed samples in buffer solutions with different pH values were evaluated spectrophotometrically using the CIELAB color space. The color fastness to rubbing, washing, and light, and the water and oil repellency of the dyed fabrics were determined according to valid SIST EN ISO standards The results showed that the unfinished dyed polyamide 6 fabric undergoes a reversible color change faster and more clearly than the finished dyed polyamide 6 fabric. The dyed polyamide 6 fabric had good color fastness to rubbing and domestic and com. laundering, while the color fastness to light was poor. In addition, the dyed polyamide 6 fabric was pH-sensitive, despite dye degradation under xenon light, regardless of whether it was finished.

This literature about this compound(76-60-8)Application of 76-60-8has given us a lot of inspiration, and I hope that the research on this compound(3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Formula: C21H14Br4O5S. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide, is researched, Molecular C21H14Br4O5S, CAS is 76-60-8, about Intracellular prostaglandin E2 contributes to hypoxia-induced proximal tubular cell death. Author is Garcia-Pastor, Coral; Benito-Martinez, Selma; Bosch, Ricardo J.; Fernandez-Martinez, Ana B.; Lucio-Cazana, Francisco J..

Proximal tubular cells (PTC) are particularly vulnerable to hypoxia-induced apoptosis, a relevant factor for kidney disease. We hypothesized here that PTC death under hypoxia is mediated by cyclo-oxygenase (COX-2)-dependent production of prostaglandin E2 (PGE2), which was confirmed in human proximal tubular HK-2 cells because hypoxia (1% O2)-induced apoptosis (i) was prevented by a COX-2 inhibitor and by antagonists of prostaglandin (EP) receptors and (ii) was associated to an increase in intracellular PGE2 (iPGE2) due to hypoxia-inducible factor-1α-dependent transcriptional up-regulation of COX-2. Apoptosis was also prevented by inhibitors of the prostaglandin uptake transporter PGT, which indicated that iPGE2 contributes to hypoxia-induced apoptosis (on the contrary, hypoxia/reoxygenation-induced PTC death was exclusively due to extracellular PGE2). Thus, iPGE2 is a new actor in the pathogenesis of hypoxia-induced tubular injury and PGT might be a new therapeutic target for the prevention of hypoxia-dependent lesions in renal diseases.

From this literature《Intracellular prostaglandin E2 contributes to hypoxia-induced proximal tubular cell death》,we know some information about this compound(76-60-8)Formula: C21H14Br4O5S, but this is not all information, there are many literatures related to this compound(76-60-8).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Sun, Zhongyu; Fan, Jiajin; Wang, Jiayue; Wang, Fei; Nie, Lei; Li, Lian; Dong, Qin; Li, Can; Du, Ranran; Quan, Shuang; Zang, Hengchang published the article 《Assessment of the human albumin in acid precipitation process using NIRS and multi-variable selection methods combined with SPA》. Keywords: human albumin acid precipitation NIRS projection algorithm.They researched the compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide( cas:76-60-8 ).Product Details of 76-60-8. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:76-60-8) here.

Human albumin (HA) content was determined by near IR spectroscopy (NIRS), which was an process anal. technol. (PAT) tool, to realize process monitoring during acid precipitation Eight batches of acid precipitation process samples were simulated in laboratory, and HA contents were determined by bromocresol green (BCG) method. Five batches were selected as calibration set and three batches were selected as validation set to build partial least squares regression (PLSR) model of HA content. Before the establishment of PLSR model, partial samples and different variable selection methods were compared in details and 35 variables were finally selected. The successive projection algorithm (SPA) combined with the multi-variable selection methods (CC, UVE, CARS, SCARS, FiPLS, MWPLS, BiPLS) could obtain more useful information than the single method. The RMSECV and RMSEP values of the optimal PLSR model were 0.7038 g/L and 0.5893 g/L, resp. Meanwhile, NIRS was an effective tool and could be successfully used for quant. monitoring during acid precipitation process. To some extent, it could provide theor. supports for quality control with a fast, nondestructive and low-cost NIRS in monitoring the complex biol. production process.

From this literature《Assessment of the human albumin in acid precipitation process using NIRS and multi-variable selection methods combined with SPA》,we know some information about this compound(76-60-8)Product Details of 76-60-8, but this is not all information, there are many literatures related to this compound(76-60-8).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Related Products of 76-60-8. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide, is researched, Molecular C21H14Br4O5S, CAS is 76-60-8, about Fe/Co-chalcogenide-stabilized Fe3O4 nanoparticles supported MgAl-layered double hydroxide as a new magnetically separable sorbent for the simultaneous spectrophotometric determination of anionic dyes. Author is Behbahani, Elham Sadati; Dashtian, Kheibar; Ghaedi, Mehrorang.

Magnesium-aluminum layered double hydroxide (MgAl-LDH) supported on Fe3O4-SiO2 which stabilized and modified by CoS-FeS chalcogenide was prepared and characterized by FT-IR, XRD, FE-SEM, EDS and, VSM anal. Subsequently, this prepared material was applied in a dispersive solid-phase extraction (DSPE) system for simultaneous preconcentration and determination of trace levels of disulfine blue (DSB) and bromocresol green (BCG) anionic dyes from aqueous solutions which method was followed by UV-vis spectrophotometry detection. Central composite design (CCD) was applied to optimize the contribution of operational parameters including pH, sorbent dosage, sonication extraction time, type, volume and eluent concentration on system performance. Under optimized conditions, detection and quantification limits were obtained to be 0.033 mg L-1 and 0.109 mg L-1 for DSB and 0.037 and 0.123 mg L-1 for BCG, resp., as well as, good linearity was obtained. This novel and interesting extraction approach seem to be fast and efficient procedure for the extraction of anionic dyes from aqueous samples. The kinetics and the adsorption isotherms of dyes reveal their rapid adsorption, following a with a pseudo-first-order kinetics and Freundlich adsorption isotherm model.

From this literature《Fe/Co-chalcogenide-stabilized Fe3O4 nanoparticles supported MgAl-layered double hydroxide as a new magnetically separable sorbent for the simultaneous spectrophotometric determination of anionic dyes》,we know some information about this compound(76-60-8)Related Products of 76-60-8, but this is not all information, there are many literatures related to this compound(76-60-8).

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Name: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide, is researched, Molecular C21H14Br4O5S, CAS is 76-60-8, about Acidity constant of pH indicators in the supramolecular systems studied by two CE-based methods compared using the RGB additive color model.

Acid-base properties of methyl orange, bromocresol green, bromophenol blue, and bromothymol blue were thoroughly investigated in the past due to their application as colorimetric pH indicators. However, it is still unknown how these properties change upon the supramol. host-guest interactions. Owing to the growing interest in using supramol. host-guest interactions to reach expected modification of various physicochem. properties of guests, we decided to address this question in the present article. We estimated the shifts of pKa values induced by diverse hosts (cyclodextrins, cucurbiturils, calixarenes, micelles, and serum albumin) and performed a thermodn. anal. of the selected systems. To make a deeper insight, we confronted the aforementioned dyes with the other kinds of mols. studied by us in the past. In overall, the results obtained demonstrate a large multiplicity of possible pKa behaviors, their poor predictability, and the existence of subtle structure-acidity relationships. In addition, we observed three thermodynamically different mechanisms of pKa alteration. Therefore, more studies are needed to bring closer the promising perspective of a programmable acidity’s tuning. Our methodol. was based on capillary electrophoresis (CE) applied in two parallel variants: a classical method based on the fitting of a nonlinear function, and an alternative two-value method (TVM), which requires over twice less measurements to estimate pKa. To identify the optimal approach for further studies, both methods were comprehensively compared and discussed based on the RGB additive color model, a user-friendly scale that integrates three primary aspects of an anal. method: anal. performance, green chem., and practicality.

There is still a lot of research devoted to this compound(SMILES：CC1=C(Br)C(O)=C(Br)C=C1C2(C3=CC(Br)=C(O)C(Br)=C3C)C4=CC=CC=C4S(O2)(=O)=O)Name: 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide, and with the development of science, more effects of this compound(76-60-8) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles