Let’s face it, organic chemistry can seem difficult to learn, Computed Properties of https://www.ambeed.com/products/80-46-6.html, Especially from a beginner’s point of view. Like 80-46-6, Name is 4-tert-Amylphenol, molecular formula is indole-building-block, belongs to indole-building-block compound. In a document, author is Han, Qingshuai, introducing its new discovery.
In the past decades, C-H oxidative olefination of indole at C-2, C-3, C-4 and C-7 positions was well addressed. We report here a rhodium-catalyzed NH-indole-directed ortho C-H bond olefination of 2-arylindoles. This cross-dehydrogenative-coupling proved to be broad in substrate scope, tolerating a variety of functional groups. The synthesis of 6H-isoindolo[2,1-]indoles via rhodium-catalyzed ortho C-H olefination and subsequent intramolecular aza-Michael reaction of 2-arylindoles was also demonstrated.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles