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Metal-catalyzed dehydrogenative synthesis of pyrroles and indoles from alcohols

This review is focused on the synthesis of various classes of pyrroles and indoles from alcohols as substrates or intermediates. Metal-induced dehydrogenation converts primary or secondary alcohols into the related carbonyl compounds (aldehydes or ketones), which can undergo in situ inter- or intramolecular attack by a carbon or nitrogen nucleophile to afford a new C?C or C?N bond, respectively. The formation of these bonds is the key step in the construction of the pyrrole and indole framework. Thus, pyrroles are obtained in good yields by dehydrogenative cyclization of beta-hydroxyenamines, and dehydrogenative N-heterocyclization of amines with diols, High yields of pyrroles are also obtained by reacting 2-amino alcohols with alcohols or ketones. Relevant is also the synthesis of pyrroles by a three-component reaction. Indoles are formed in high yields by intramolecular cyclization of 2-amino- and 2-nitrophenylethyl alcohols, and 2-aminobenzyl alcohols. Moreover, indole derivatives are also conveniently obtained by reaction of glycols or alcohols with anilines or phenyl hydrazine, respectively.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N1821 – PubChem

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Related Products of 80-73-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 80-73-9, 1,3-Dimethylimidazolidin-2-one, introducing its new discovery.

Fabrication of poly(bis-benzimidazole imide) fibers with enhanced mechanical properties and high limit oxygen indexes

A kind of diamine monomer 2,2?-p-phenylenebis (5-aminobenzimidazole) (PBABI) with bis-benzimidazole moiety was synthesized and a facile two-step wet-spinning method was employed to fabricate a series of polyimide fibers containing bis-benzimidazole units (PBIPI) with the 3,3?,4,4?-biphenyltetracarboxylic anhydride (BPDA), p-Phenylenediamine (p-PDA) and self-synthesized PBABI as the monomers. The structures and purity of self-synthesized PBABI was characterized in detail. Various temperatures for thermal-drawn process were studied and the 2D-WAXD showed that the higher the temperature for thermal-drawn process, the more orderly of the polymer chains. Attributed to the stronger intermolecular hydrogen bonding forces combined with the orientation and arrangement of molecular chains, the as-spun PBIPI fiber displayed improved mechanical properties with the tensile strength of 1.97 GPa and the initial modulus 59.5 GPa. Furthermore, the PBIPI fiber also showed improved thermal stability and flame resistance properties due to the existent of benzimidazole units. Correspondingly, the glass transition temperature (Tg) and the temperature at the maximum degradation rate (Td-max) of the PBIPI fiber in nitrogen increased by 76 C and 17 C respectively and the limit oxygen index (LOI) enhanced by 13%, making these novel polymeric fibers as good thermo-resistant and flame-retardant fiber in fire-fighting domain.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N1978 – PubChem

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Chemistry is traditionally divided into organic and inorganic chemistry. Formula: C5H10N2O, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 80-73-9

Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds. Sublimation, Vaporization and Fusion Enthalpies From 1880 to 2015. Part 1. C1-C10

A compendium of phase change enthalpies published in 2010 is updated to include the period 1880-2015. Phase change enthalpies including fusion, vaporization, and sublimation enthalpies are included for organic, organometallic, and a few inorganic compounds. Part 1 of this compendium includes organic compounds from C1-C10. Part 2 of this compendium, to be published separately, will include organic and organometallic compounds from C11 to C192. Sufficient data are presently available to permit thermodynamic cycles to be constructed as an independent means of evaluating the reliability of the data. Temperature adjustments of phase change enthalpies from the temperature of measurement to the standard reference temperature, T = 298.15 K, and a protocol for doing so are briefly discussed.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N1783 – PubChem

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Magnesium based coordination polymers: Syntheses, structures, properties and applications

Coordination polymers (CPs) and/or metal?organic frameworks (MOFs) have been a hot research topic over the past two decades. Many CPs structures based on p-, d-, f- and some s-block metal ions, including magnesium (Mg), have been reported. While not as common in the literature as some other metals, magnesium-based CPs have unique potential applications, largely because of the specific properties of the Mg metal. Mg-CPs can possess high gravimetric gas storage capacities due to the metal’s low density, can facilitate base-catalyzed reactions as a result of its strong Lewis acidity, and have shown high performance as electrode materials due to its high-density energy storage capacity. This review intends to provide an overview on the research related to Mg-CPs in the past twenty years. We will briefly describe various structural features, important properties, and potential applications of the Mg-CPs reported during this time period. A number of representative examples will be discussed for each type of important application.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N2168 – PubChem

Extracurricular laboratory:new discovery of 80-73-9

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Investigation of a family of structurally-related guanidinium ionic liquids through XPS and thermal analysis

A family of structurally-related guanidinium bistriflimide ionic liquids has been prepared and characterized. TGA analyses showed a high thermal stability for all the proposed ionic liquids while DSC and XPS analyses divided them into distinct subsets depending on whether one or more constraining cycles were present. The results obtained highlighted the influence of the cation structure on some of the physico-chemical properties and thus the possibility to tune them by selecting proper substituents. The solvatochromic parameters of a selected guanidinium IL have also been studied.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N2034 – PubChem

Brief introduction of 80-73-9

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Synthetic Route of 80-73-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.80-73-9, Name is 1,3-Dimethylimidazolidin-2-one, molecular formula is C5H10N2O. In a Patent£¬once mentioned of 80-73-9

Process for the preparation of 11-oxaprostaglandins and intermediates therein

For the preparation of an 11-oxaprostaglandin such as [2R,(1E,3R),3S,(4Z),4R)]-7-{tetrahydro-2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-4-hydroxy-3-furanyl}-4-heptenoic acid and its ester derivatives, a novel process uses a novel enantiomerically enriched compound for formula (1) wherein the bond between carbon atoms y and z is either a single or double bond; R1 is selected from vinyl, trialkylsilylethynyl, a formyl group protected as an acetal, or a protected hydroxymethyl group; R2 is C1-5 alkyl, optionally substituted at the terminus with an aryloxy or alkoxy group; and R3-R6 are independently selected from C1-6 alkyl and C6-10 aryl. 1

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N1721 – PubChem

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Synthetic Route of 80-73-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.80-73-9, Name is 1,3-Dimethylimidazolidin-2-one, molecular formula is C5H10N2O. In a article£¬once mentioned of 80-73-9

Synthesis of acylguanidine analogues: inhibitors of ADP-induced platelet aggregation

Routine screening of compounds for inhibition of ADP-induced platelet aggregation in vitro revealed that 1′-hexamethylenebis[3-cyclohexyl-3-[(cyclohexylimino)(4-morpholinyl)methyl] urea] was active and represented the first example of a bis(acylguanidine) with possible antithrombotic activity. In order to develop a structure-activity relationship for this class of compounds, we synthesized a number of new bis(acylguanidines). These were tested in vitro, and several analogues were also active. Ex vivo testing revealed that compounds 22, 41, 58, and 70-73 were orally active in rats or guinea pigs.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N2137 – PubChem

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80-73-9, Name is 1,3-Dimethylimidazolidin-2-one, belongs to imidazolidine compound, is a common compound. Quality Control of 1,3-Dimethylimidazolidin-2-oneIn an article, once mentioned the new application about 80-73-9.

A chemometrics approach to predict the dispersibility of graphene in various liquid phases using theoretical descriptors and solvent empirical parameters

This work focuses on the dispersibility of graphene in different solvent phases. A chemometrics study was performed on the dispersibility of graphene in liquid phases. Two multilinear regression models were constructed using theoretical and empirical parameters of the solvents. The model based on solvent empirical parameters resulted in better statistical qualities as well as better description ability. This model which was constructed by empirical parameters covered 85% and 90% of the variance in the train and test sets respectively. Based on the molecular descriptors and empirical parameters appeared in the models, it was suggested that some weak van der Waals interaction would help in the dispersibility of graphene. Among these interactions, dispersive interactions, in comparison with H-bonding and polar interactions, might have a more significant role in increasing the graphene dispersibility.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N2183 – PubChem

Simple exploration of 1,3-Dimethylimidazolidin-2-one

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 80-73-9, and how the biochemistry of the body works.Related Products of 80-73-9

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Aralkylamine derivatives, and fungicides containing the same

Disclosed are a compound of the formula (I) or an acid addition salt thereof: STR1 wherein Q represents R1 , R2, R3, R4, R5, R6, n and z are defined as in the specification, preparation method thereof and fungicides containing the same.

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Reference£º
Imidazolidine – Wikipedia,
Imidazolidine | C3H8N1677 – PubChem