902772-13-8, 5-Bromo-1H-indole-2-carbonitrile is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
902772-13-8, Anhydrous CH2Cl2 (270 mL), Et3N (4.86 mL, 34.7 mmol) and pyridine (2.82 mL, 34.7 mmol) were added to 5-bromoindole-2-carbom’trile (3.83 g, 17.3 mmol; see step (b) above), Cu(OAc)2 (6.29 g, 34.7 mmol), 3 A molecular sieves (ca. 7 g) and4-cyclopentyloxyphenylboronic acid (7.15 g, 34.7 mmol). The mixture was stirred vigorously at rt for 72 h and filtered through Celite. The solids were washed withEtOAc, and the combined filtrates concentrated and purified by chromatography to afford the sub-title compound (3.87 g, 59%).
902772-13-8 5-Bromo-1H-indole-2-carbonitrile 68473340, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Patent; BIOLIPOX AB; WO2006/77367; (2006); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles