Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 94-26-8, Name is Butyl 4-hydroxybenzoate, molecular formula is C11H14O3, belongs to indole-building-block compound. In a document, author is Zhang, Dongdong, introduce the new discover, Application In Synthesis of Butyl 4-hydroxybenzoate.
Isatindigoside A and B (1 – 2), two new indole alkaloid glycosides along with five known ones (3 – 7) were obtained from the roots of I. tinctoria. Their structures were determined as isatindigoside A (1), isatindigoside B (2), isatindosulfonicacid A 3-O-beta-D-glucopyranoside (3), indole-3-acetonitrile 6-O-beta-D-glucopyranoside (4), isatindigobisindoloside A (5), isatindigobisindoloside B (6) isatindigobisindoloside F (7), by physicochemical properties and spectroscopic methods including 1 D, 2 D NMR, IR, HR-ESI-MS data. Nitric oxide (NO) inhibitory activities of all of the isolated compounds (1 – 7) were also evaluated. Compounds 2 and 7 showed inhibitory effects against LPS-stimulated RAW 264.7 cells with IC50 values of 27.6 mu M and 18.8 mu M, respectively. [GRAPHICS] .
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles