HPLC of Formula: C8H8O2. In 2020.0 CHINESE J CHEM published article about ELECTROPHILIC MONOFLUOROMETHYLATION; NUCLEOPHILES; FLUORINE; TRIFLUOROMETHYLATION; DIFLUOROMETHYLATION; CH2F in [Hong, Xin; Liu, Yafei; Shen, Qilong] Univ Chinese Acad Sci, Chinese Acad Sci, Ctr Excellence Mol Synth, Key Lab Organofluorine Chem,Shanghai Inst Organ C, 345 Lingling Rd, Shanghai 200032, Peoples R China; [Lu, Long] Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Organ Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China in 2020.0, Cited 39.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.
The Summary of main observation and conclusionStructure-reactivity study of a family of electrophilic monofluoromethylating reagents based on sulfonium ylide skeleton with different steric hindrance and electron-withdrawing properties was described. These studies led us to discover two highly reactive reagents 3 with a cyclic malonate backbone and 6 with an electron-poor 1,1,1,5,5,5-hexafluoropentane-2,4-dione backbone. The high reactivity of reagent 6 allowed to highly selectively access either C-monofluoromethylated or O-monofluoromethylated beta-ketoesters in high yields by the use of different bases. In addition, reactions of reagent 3 with a variety of nucleophiles including phenols, carboxylic acids, thiophenols or heteroaryl nucleophiles occurred in full conversion within 10 min at room temperature and the scopes for these reactions were reported in detail.
Welcome to talk about 99-93-4, If you have any questions, you can contact Hong, X; Liu, YF; Lu, L; Shen, QL or send Email.. HPLC of Formula: C8H8O2
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles