Chen, Cong; Jiao, Hongjian; Chen, Di; Tang, Tao; Xu, Ze-Feng; Duan, Shengguo; Li, Chuan-Ying published an article in 2022, the title of the article was Access to tetrahydrocarbazoles and pyrrolo[3,4-b]carbazoles through sequential reactions of triazoles and indoles.Application In Synthesis of 1,5-Dimethyl-1H-indole-2-carbaldehyde And the article contains the following content:
Tetrahydrocarbazoles I (R = H, Me; R1 = H, OMe, F, Cl, etc.; R2 = H, Me; R3 = H, Me; R4 = Me, allyl; R5 = Et, t-Bu; R6 = Me, Ts, benzenesulfonyl, etc.; R7 = Ac, Boc, Bz, etc.) and pyrrolo[3,4-b]carbazoles II could be synthesized conveniently through sequential reactions of ester-tethered 1-sulfonyl-1,2,3-triazoles III and indoles IV. The reaction conditions were mild and the procedures were quite simple. Moreover, the key intermediate α,β-unsaturated imine acted as a [2C] synthon in the [4 + 2] cycloaddition reaction, and the imino group could be used as a nucleophile to construct the fourth ring. The experimental process involved the reaction of 1,5-Dimethyl-1H-indole-2-carbaldehyde(cas: 883526-76-9).Application In Synthesis of 1,5-Dimethyl-1H-indole-2-carbaldehyde
The Article related to tetrahydrocarbazole preparation, pyrrolocarbazole preparation, indole ester sulfonyl triazole diels alder reaction, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Application In Synthesis of 1,5-Dimethyl-1H-indole-2-carbaldehyde
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles