On September 5, 2014, Chen, Hui; Wang, Jiang; Zhou, Shengbin; Liu, Hong published an article.COA of Formula: C9H9NO2 The title of the article was Asymmetric Synthesis of Chiral Heterocyclic Amino Acids via the Alkylation of the Ni(II) Complex of Glycine and Alkyl Halides. And the article contained the following:
An investigation into the reactivity profile of alkyl halides led to the development of a new method for the asym. synthesis of chiral heterocyclic amino acids. This protocol involves the asym. alkylation of the Ni(II) complex of glycine, [NiL] (H2L = N-[phenyl[2-[[[(2S)-1-(phenylmethyl)-2-pyrrolidinyl]carbonyl]amino]phenyl]methylene]-glycine), to form an intermediate, which then decomposes to form valuable chiral amino acids in high yields and with excellent diastereoselectivity. The chiral amino acids underwent a smooth intramol. cyclization process to afford the valuable chiral heterocyclic amino acids in high yields and enantioselectivities. This result paves the way for the development of a new synthetic method for chiral heterocyclic amino acids. The experimental process involved the reaction of H-Idc-OH(cas: 79815-20-6).COA of Formula: C9H9NO2
The Article related to nickel pyrrolidinylcarbonylaminophenylmethyleneglycine complex preparation alkylation, asym preparation chiral heterocyclic amino acid, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.COA of Formula: C9H9NO2
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles