A copper iodide-catalyzed coupling reaction of benzofuran-3(2H)-ones with amines: an approach to 伪-ketoamides was written by Chen, Rongxiang;Jia, Ruo-Ling;Li, Wenbo;Zhao, Wei;Wang, Kai-Kai;Wang, Zhan-Yong;Ma, Xueji;Dai, Wei;Sun, Aili. And the article was included in Organic & Biomolecular Chemistry in 2021.Product Details of 16800-68-3 This article mentions the following:
A CuI-catalyzed coupling reaction of benzofuran-3(2H)-ones with amines has been well established for the direct synthesis of 伪-ketoamides. This process involves C-O bond cleavage and C=O/C-N bond formation. Mechanism studies indicated that this 伪-ketoamide formation reaction may involve a free radical process. In the experiment, the researchers used many compounds, for example, 1-Acetylindolin-3-one (cas: 16800-68-3Product Details of 16800-68-3).
1-Acetylindolin-3-one (cas: 16800-68-3) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Product Details of 16800-68-3
Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles