Corrieri, Matteo published the artcilePractical and sustainable preparation of pyrrolo[2,3-b]indoles by Cu/Fe catalyzed intramolecular C(sp2)-H amination, Name: 4-(Benzyloxy)-1-methyl-1H-indole, the main research area is pyrrolo indole copper iron catalyzed intramol amination.
A practical, robust and chemoselective approach toward the synthesis of pyrrolo[2,3-b]indoles via direct intramol. C-H bond amination of α-indolylhydrazones has been achieved. This base- and oxidant-free chemoselective transformation relies on a Cu/Fe co-catalyst system that operates at 50 °C in air with water as the only reaction medium. The easy product isolation together with the recyclable catalyst aqueous system (reused at least five times, maintaining over 50% of its catalytic activity) can provide an effective environmentally benign approach to fused N-heterocycles of remarkable interest in pharmaceutical and medicinal chem. The ability of the hydrazone residue to act as a chelating/directing group as well as an aminating agent guarantees the success of this C-H functionalization.
Green Chemistry published new progress about Amination. 13523-93-8 belongs to class indole-building-block, name is 4-(Benzyloxy)-1-methyl-1H-indole, and the molecular formula is C16H15NO, Name: 4-(Benzyloxy)-1-methyl-1H-indole.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles