Corrieri, Matteo published the artcileSynthesis of Azacarbolines via PhIO2-Promoted Intramolecular Oxidative Cyclization of α-Indolylhydrazones, Safety of 4-(Benzyloxy)-1-methyl-1H-indole, the main research area is pyridazinoindole green preparation; alpha indolylhydrazone intramol oxidative cyclization iodylbenzene.
An unprecedented synthesis of polysubstituted indole-fused pyridazines (azacarbolines) I [R1 = H, Me, n-Pr, Bn; R2 = 6-Me, 5-Cl, 6-MeO, etc.; R3 = Ph, CO2Me, CO2Et, etc.; R4 = Me, Et, n-Pr, H2CCO2Et] from α-indolylhydrazones II under oxidative conditions using a combination of iodylbenzene (PhIO2) and trifluoroacetic acid (TFA) had been developed. This transformation was conducted without the need for transition metals, harsh conditions, or an inert atm.
Journal of Organic Chemistry published new progress about Alkanes Role: RCT (Reactant), RACT (Reactant or Reagent) (azo). 13523-93-8 belongs to class indole-building-block, name is 4-(Benzyloxy)-1-methyl-1H-indole, and the molecular formula is C16H15NO, Safety of 4-(Benzyloxy)-1-methyl-1H-indole.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles