Curzon, G. published the artcileA method for the determination of urinary indoxyl sulfate (indican), Product Details of C8H6KNO4S, the publication is Clinica Chimica Acta (1962), 657-63, database is CAplus and MEDLINE.
The method is based on the Ehrlich reaction of indoxyl sulfate with p-dimethylaminobenzaldehyde in acid solution When the solution is made alk., an intense red color is produced. This is extracted into petr. ether, in which it is yellow, and determined colorimetrically at 464 mμ. Urea is the only substance which interferes significantly. Thus, urine determinations are corrected for urea interference by multiplying by a factor of 1.18. Using this corrected factor, exptl. found recoveries of added K indoxyl sulfate from 10 urines (50 γ/ml. urine) varied from 94 to 108%. Normal subjects excreted 48.2 ± 19.1 mg. K indoxyl sulfate per 24 hrs.
Clinica Chimica Acta published new progress about 2642-37-7. 2642-37-7 belongs to indole-building-block, auxiliary class Indole,Salt,Sulfonate,Inhibitor,Inhibitor, name is Potassium 1H-indol-3-yl sulfate, and the molecular formula is C8H6KNO4S, Product Details of C8H6KNO4S.
Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles