Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideOn September 30, 1988 ,《Reductive dephthalimidation: a mild and efficient method for the N-phthalimido deprotection during oligosaccharide synthesis》 was published in Journal of Carbohydrate Chemistry. The article was written by Dasgupta, Falguni; Garegg, Per J.. The article contains the following contents:
NaBH4 cleaves the phthalimido group in suitably protected carbohydrates. Best results are obtained with 8-10 M excess NaBH4. Thus, phthalimidoglucopyranoside I (RR1N = phthalimido) (0.17 mmol) in Me2CHOH-H2O was treated with 1.74 mmol NaBH4 (4 lot added over 4-6 h at room temperature). The product was acetylated with AcOH-pyridine to give 77% I (RR1N = AcNH). The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)
Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles