Lewis Base Catalyzed, Enantioselective, Intramolecular Sulfenoamination of Olefins was written by Denmark, Scott E.;Chi, Hyung Min. And the article was included in Journal of the American Chemical Society in 2014.Application In Synthesis of 2-(Phenylthio)isoindoline-1,3-dione This article mentions the following:
A method for the enantioselective, intramol. sulfenoamination of various olefins has been developed using a chiral BINAM-based selenophosphoramide Lewis base catalyst [e.g., I + PhthSPh → II (93% yield, e.r. 93.6:6.4)]. Terminal and trans disubstituted alkenes afforded pyrrolidines, piperidines, and azepanes in high yields and high enantiomeric ratios via enantioselective formation and subsequent stereospecific capture of the thiiranium intermediate with the pendant tosyl-protected amine. In the experiment, the researchers used many compounds, for example, 2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4Application In Synthesis of 2-(Phenylthio)isoindoline-1,3-dione).
2-(Phenylthio)isoindoline-1,3-dione (cas: 14204-27-4) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Application In Synthesis of 2-(Phenylthio)isoindoline-1,3-dione
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles