Rapid One-Pot Access to Unique 3,4-Dihydrothiopyrano[3,4-b]indol-1(9H)-imines via Bi(OTf)3-Catalysed Tandem Friedel-Crafts Alkylation/Thia-Michael Addition was written by Dethe, Dattatraya H.;Boda, Vijay Kumar;Mandal, Anupam. And the article was included in European Journal of Organic Chemistry in 2018.Name: 4-Bromoindole-3-acetic Acid This article mentions the following:
A highly efficient and atom economical one-pot annulation strategy for tetrahydrothiopyrano[3,4-b]indoles, e.g., I, is presented. This protocol involves a Bi(OTf)3 catalyzed tandem Friedel-Crafts alkylation and intramol. thia-Michael addition reactions to furnish target mols. in an efficient manner. The method works effectively on substrates with unprotected indoles and also it is successfully employed to make tetrahydrothiepino[3,4-b]indoles. The scaffolds synthesized are diverse and first of the kind. The reaction is practically simple with broad substrate scope and vast functional group compatibility. In the experiment, the researchers used many compounds, for example, 4-Bromoindole-3-acetic Acid (cas: 89245-41-0Name: 4-Bromoindole-3-acetic Acid).
4-Bromoindole-3-acetic Acid (cas: 89245-41-0) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Name: 4-Bromoindole-3-acetic Acid
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles