The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 27113-22-0, Name is Paradol, SMILES is CCCCCCCC(CCC1=CC=C(O)C(OC)=C1)=O, in an article , author is Mane, Vaijinath, once mentioned of 27113-22-0, Safety of Paradol.
Synthesis of Functionalized Thieno[2,3-b] indoles via One-Pot Reaction of Indoline-2-thiones with Morita-Baylis-Hillman and Rauhut-Currier Adducts of Nitroalkenes
A straightforward protocol for the synthesis of functionalized thieno[2,3-b] indoles by base-mediated [3 + 2]annulation of indoline-2-thione with Morita-Baylis-Hillman and Rauhut-Currier adducts of nitroalkenes is described. Complete regioselectivity, broad substrate scope, and mild reaction conditions make this strategy very valuable. Moreover, the thieno[2,3-b] indoles comprising functional groups such as hydrazine and ketoalkyl moieties are amenable for further synthetic elaboration.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles