Chemistry is an experimental science, Application In Synthesis of 5-Bromo-1H-indole-3-carbaldehyde, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 877-03-2, Name is 5-Bromo-1H-indole-3-carbaldehyde
Method for synthesizing indole -3 – formaldehyde compounds (by machine translation)
The invention relates to a synthetic indole – 3 – formaldehyde compounds, which belongs to the technical field of organic synthesis. The invention will be indole compound, hexamethylene tetramine, crystalline aluminum trichloride, N, N – dimethyl formamide in proportion in 120 C reaction under the condition of 1 – 20 the H, then filtered, washing, filtering, concentrating, column chromatography purification and other after-treatment technology, make the refined indole – 3 – formaldehyde compound. The invention overcomes the indole – 3 – benzaldehyde compound of preparation need to use not stabilized peroxide, and for a long time under the high temperature reaction of the defect. And the invention uses the advantages of simple equipment, product yield is high, the resulting yield of a target product can be up to 94%. In addition, the invention relates to a low reaction conditions, less catalyst levels, low energy consumption, the post treatment process is simple and easy to use, without the need of using a high dosage of acid or alkali, post-processing the solvent can be recovered and recycled, industrial “three wastes” is discharged little, suitable for large-scale production. (by machine translation)
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application In Synthesis of 5-Bromo-1H-indole-3-carbaldehyde, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 877-03-2, in my other articles.
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles