Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 2444-46-4, Name is N-Vanillylnonanamide, molecular formula is C17H27NO3, belongs to indole-building-block compound, is a common compound. In a patnet, author is Yan, Jiyao, once mentioned the new application about 2444-46-4, Computed Properties of C17H27NO3.
A Study of the Reactivity of (Aza-)Quinone Methides in Selective C6-Alkylations of Indoles
The kinetic and thermodynamic features of indole N1- and C6-alkylation reactions with (aza-)quinone methides have been studied. The electrophilic reactivity of these quinone methides have also been compared for the first time by both experiments and DFT calculations. The indole N1-alkylation is typically kinetically favorable, but the C6-alkylation is more thermodynamically favorable. With suitable conditions, the C6-alkylation could be achieved with high efficiency and selectivity. Among these quinone methides, the reactivity increases from aza-p-QMs to o-QMs. The results not only provide access to a range of valuable triarylmethanes, but also guide future development of new reactions with these versatile electrophiles.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 2444-46-4. The above is the message from the blog manager. Computed Properties of C17H27NO3.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles