Downstream Synthetic Route Of 100-51-6

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In 2020.0 J ORG CHEM published article about REDUCTIVE AMINATION; NUCLEOPHILIC-SUBSTITUTION; TRANSFER HYDROGENATION; ALLYLIC ALCOHOLS; AMINES; SULFONAMIDES; ACID; HYDROAMINATION; ALDEHYDES; KETONES in [Guru, Murali Mohan; Thorve, Pradip Ramdas; Maji, Biplab] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741246, India in 2020.0, Cited 92.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. Safety of Benzyl Alcohol

A sustainable boron-based catalytic approach for chemoselective N-alkylation of primary and secondary aromatic amines and amides with primary, secondary, and tertiary benzylic alcohols has been presented. The metal-free protocol operates at low catalyst loading, tolerates several functional groups, and generates H2O as the sole byproduct. Preliminary mechanistic studies were performed to demonstrate the crucial role of boron catalyst for the activation of the intermediate dibenzyl ether and to identify the rate-determining step.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles