With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1074-87-9,(1H-Indol-7-yl)methanol,as a common compound, the synthetic route is as follows.
iv) 7-Indolecarboxaldehyde Solid pyridinium dichromate (1.77 g, 5.1 mmol) was added in portions over 3 hours to a stirred solution of 7-indolemethanol (0.5 g, 3.4 mmol) in dichloromethane (50 ml). The mixture was stirred for a further 2 hours then filtered through a pad of Celite filter aid. The filtrate was evaporated and the residue purified by chromatography on silica in ethyl acetate-hexane (1:3).
As the paragraph descriping shows that 1074-87-9 is playing an increasingly important role.
Reference£º
Patent; Lilly Industries Limited; US5281593; (1994); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles