1601-18-9, Methyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Methyl-1 -hydro-indol-3-yl) acetate (0.71 g, 2 mmol) was dissolved in 10 mL of a solution of methylmagnesium bromide After water, methanol was added, and 3.5 mL of the above-mentioned hydroxylamine potassium (NH2OK) solution was added thereto. After 0.5 hours, methanol was distilled off, and the solution was acidified to pH 3-4 with 2 mol / L hydrochloric acid solution. The mixture was extracted with ethyl acetate and the combined ethyl acetate layer was washed with saturated brine, dried over anhydrous magnesium sulfate and evaporated to dryness to give The crude product was recrystallized from ethyl acetate to give 0.32 g of a white powder. Yield: 44%., 1601-18-9
The synthetic route of 1601-18-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Qingdao University; Zhang, Lei; Han, Yantao; Bian, Jiang; Zhang, Jian; Xu, Wenfang; (11 pag.)CN105418480; (2016); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles