16066-91-4, 5-Iodo-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The reaction was performed in high pressure autoclave of 100 mL capacity manufactured by M/s Amar Industries. Toluene (10 mL), Pd(acac)2 (3 mg, 1 mol %), and dppm (7.7 mg, 2 mol %) were added to the autoclave reactor. To this solution iodobenzene (204 mg, 1.0 mmol), n-hexadecane (50 mg, internal GC standard), TMEDA (N,N,N’,N’-tetramethylethylenediamine, 1 equiv) were added. The mixture was flushed twice with CO/H2 1:1, then synthetic gas pressure was adjusted to 10 bar and the mixture was heated at 100 C for 10 h. After completion of reaction, the reaction mixture was cooled to room temperature. The light yellow colored solution was evaporated and residue obtained was purified by column chromatography (silica gel, mesh size 60-120) using pet ether/ethyl acetate (95:05) as eluent to get the desired formylated product., 16066-91-4
The synthetic route of 16066-91-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Singh, Abhilash S.; Bhanage, Bhalchandra M.; Nagarkar, Jayashree M.; Tetrahedron Letters; vol. 52; 18; (2011); p. 2383 – 2386;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles