2795-41-7, 6-Fluoroindole-3-carboxaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2 g of intermediate I-1 and 6 g of ethoxycarbonyl methylene triphenylphosphine are dissolved in 50 ml of dry acetonitrile.70 overnight.TLC showed complete conversion of the substrate.Stop the reaction,The reaction was cooled to room temperature.Add 50ml ethyl acetate and 50ml water,Extraction and separation of water layer,The organic layer is dry,concentrate,Column chromatography gave 6.1 g of intermediate I-17 (white solid, yield 85%).
2795-41-7, 2795-41-7 6-Fluoroindole-3-carboxaldehyde 262903, aindole-building-block compound, is more and more widely used in various fields.
Reference：
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Hu Youhong; Geng Meiyu; Xing Weiqiang; Ding Jian; Ai Jing; (86 pag.)CN103664895; (2018); B;,
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