Zarate, Cayetana; Yang, Haifeng; Bezdek, Mate J.; Hesk, David; Chirik, Paul J. published an article about the compound: Nickel(II) chloride ethylene glycol dimethyl ether complex( cas:29046-78-4,SMILESS:COCCOC.Cl[Ni]Cl ).HPLC of Formula: 29046-78-4. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:29046-78-4) through the article.
The synthesis and spectroscopic characterization of a family of Ni-X (X = Cl, Br, I, H) complexes supported by the bulky α-diimine chelate N,N’-bis(1R,2R,3R,5S)-(-)-isopinocampheyl-2,3-butanediimine (ipcADI) are described. Diimine-supported, three-coordinate Ni(I)-X complexes are proposed as key intermediates in a host of catalytic transformations such as C-C and C-heteroatom cross-coupling and C-H functionalization but have until now remained synthetically elusive. A combination of structural, spectroscopic, electrochem., and computational studies were used to establish the electronic structure of each monomeric [(ipcADI)NiX] (X = Cl, Br, I) complex as a Ni(I) derivative supported by a redox-neutral α-diimine chelate. The dimeric Ni hydride, [(ipcADI)Ni(μ2-H)]2, was prepared and characterized by x-ray diffraction; however, magnetic measurements and 1H NMR spectroscopy support monomer formation at ambient temperature in THF solution This Ni hydride was used as a precatalyst for the H isotope exchange (HIE) of C-H bonds in arenes and pharmaceuticals. By virtue of the multisite reactivity and high efficiency, the new Ni precatalyst provided unprecedented high specific activities (50-99 Ci/mmol) in radiolabeling, meeting the threshold required for radioligand binding assays. Use of air-stable and readily synthesized Ni precursor, [(ipcADI)NiBr2], broad functional group tolerance, and compatibility with polar protic solvents are addnl. assets of the Ni-catalyzed HIE method.
The article 《Ni(I)-X Complexes Bearing a Bulky α-Diimine Ligand: Synthesis, Structure, and Superior Catalytic Performance in the Hydrogen Isotope Exchange in Pharmaceuticals》 also mentions many details about this compound(29046-78-4)HPLC of Formula: 29046-78-4, you can pay attention to it, because details determine success or failure
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Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles