Recently I am researching about REGIOSELECTIVE OXIDATION; SELECTIVE OXIDATION; AEROBIC OXIDATION; EFFICIENT ACCESS; O-QUINONES; HYPERVALENT; TYROSINASE; COMPLEXES; SPIROLACTONIZATION; FUNCTIONALIZATION, Saw an article supported by the National Institutes of Health (NIH)United States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [R01 GM123098]; American Chemical Society Petroleum Research FundAmerican Chemical Society [DNI-56603]; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R01GM123098] Funding Source: NIH RePORTER. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Xiao, X; Greenwood, NS; Wengryniuk, SE. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone. Recommanded Product: 99-93-4
Despite their broad utility, the synthesis of ortho-quinones remains a significant challenge, in particular, access to electron-deficient derivatives remains an unsolved problem. Reported here is the first general method for the synthesis of electron-deficient ortho-quinones by direct oxidation of phenols. The reaction is enabled by a novel bidentate nitrogen-ligated iodine(V) reagent, a previously unexplored class of compounds which we have termed Bi(N)-HVIs. The reaction is extremely general and proceeds with excellent regioselectivity for the ortho over para isomer. Functionalization of the ortho-quinone products was examined, resulting in a facile one-pot synthesis of catechols, as well as the incorporation of a variety of heteroatom nucleophiles. This method represents the first synthetic application of Bi(N)-HVIs and demonstrates their potential as a platform for the further development of highly reactive, but also highly tunable, I(V) reagents.
About 4′-Hydroxyacetophenone, If you have any questions, you can contact Xiao, X; Greenwood, NS; Wengryniuk, SE or concate me.. Recommanded Product: 99-93-4
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles