A General Strategy Toward Aromatic 1,2-Ambiphilic Synthons: Palladium-Catalyzed ortho-Halogenation of PyDipSi-Arenes was written by Dudnik, Alexander S.;Chernyak, Natalia;Huang, Chunhui;Gevorgyan, Vladimir. And the article was included in Angewandte Chemie, International Edition in 2010.Name: 5-Bromo-2,3-dimethyl-1H-indole This article mentions the following:
1,2-Amphiphilic aromatic and heteroaromatic synthons were prepared by conversion of haloarenes to aryl(2-pyridinyl)diisopropylsilanes, halogenating these on the aromatic ring, and replacement of the pyridinyldiisopropylsilyl group. In the experiment, the researchers used many compounds, for example, 5-Bromo-2,3-dimethyl-1H-indole (cas: 4583-55-5Name: 5-Bromo-2,3-dimethyl-1H-indole).
5-Bromo-2,3-dimethyl-1H-indole (cas: 4583-55-5) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Name: 5-Bromo-2,3-dimethyl-1H-indole
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles