Asymmetric Dearomatizing Fluoroamidation of Indole Derivatives with Dianionic Phase-Transfer Catalyst was written by Egami, Hiromichi;Hotta, Ryo;Otsubo, Minami;Rouno, Taiki;Niwa, Tomoki;Yamashita, Kenji;Hamashima, Yoshitaka. And the article was included in Organic Letters in 2020.SDS of cas: 89245-41-0 This article mentions the following:
Asym. dearomatizing fluorocyclization of indole derivatives was investigated using a dicarboxylate phase-transfer catalyst. This reaction proceeded under mild reaction conditions to provide fluoropyrroloindoline derivatives I [R1 = H, 4-Me, 5-Cl, etc.; R2 = H, Me, Bn, etc.; R3 = SO2Me, 4-MeC6H4SO2, C6H5SO2] in a highly enantioselective manner. Various substitution patterns on the indole ring were well tolerated. To facilitate the reaction and ensure reproducibility, the addition of water was essential and its possible role was discussed. In the experiment, the researchers used many compounds, for example, 4-Bromoindole-3-acetic Acid (cas: 89245-41-0SDS of cas: 89245-41-0).
4-Bromoindole-3-acetic Acid (cas: 89245-41-0) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.SDS of cas: 89245-41-0
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles