El-Sokkary, Ramadan I.; Silwanis, Basim Azmy; Nashed, Mina A.; Paulsen, Hans published their research in Carbohydrate Research on August 15 ,1990. The article was titled 《Standardized intermediates for oligosaccharide synthesis: convenient preparation of 2-amino-2-deoxy-D-glucose derivatives and their conversion into the D-galactose analogs》.Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside The article contains the following contents:
Treating tetraacetate I (R = Ac, NPhth = phthalimido) with allyl alc. in CH2Cl2 containing FeCl3 gave I (R = CH2:CHCH2O) which was deacetylated by NaOMe-MeOH followed by benzoylation with BzCl to give 95.8% phthalimido derivative II. The latter was treated with (CF3SO2)2O in CH2Cl2 to give an intermediate 4-triflate which was converted by NaNO2-DMF to 86% galactopyranoside III, a useful glycosyl donor for oligosaccharide synthesis. The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)
Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles