Chemistry, like all the natural sciences, Formula: https://www.ambeed.com/products/1761-61-1.html, begins with the direct observation of nature— in this case, of matter.1761-61-1, Name is 5-Bromo-2-hydroxybenzaldehyde, SMILES is OC1=CC=C(Br)C=C1C=O, belongs to indole-building-block compound. In a document, author is Chen, Xue-Bing, introduce the new discover.
In this study, we detail the development of a concise and efficient three-component protocol for the regioselective synthesis of highly functionalized bis-indoles through a one-pot, two-step sequential process starting from enaminones 1, indoles 2, and acenaphthylene-1,2-dione 3 that is catalyzed by piperidine and p-methyl benzenesulfonic acid. This protocol has several advantages including simplicity of experimental operation, high efficiency of bond formation, ready availability and low cost of starting materials, environmentally benign conditions, and target molecular diversity.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 1761-61-1. Formula: https://www.ambeed.com/products/1761-61-1.html.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles