In 2019.0 J AM CHEM SOC published article about ASYMMETRIC HYDROGENATION; HIGHLY EFFICIENT; SELECTIVE HYDROGENATION; ALKENE HYDROBORATION; COBALT CATALYSIS; IRON CATALYSTS; HYDROXIDE ION; COMPLEXES; ALDEHYDES; DEHYDROGENATION in [Duan, Ya-Nan; Du, Xiaoyong; Cui, Zhikai; Zeng, Yiqun; Liu, Yufeng; Yang, Tilong; Wen, Jialin; Zhang, Xumu] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Guangdong, Peoples R China; [Duan, Ya-Nan; Du, Xiaoyong; Cui, Zhikai; Zeng, Yiqun; Liu, Yufeng; Yang, Tilong; Wen, Jialin; Zhang, Xumu] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Guangdong, Peoples R China; [Wen, Jialin] Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen 518055, Guangdong, Peoples R China in 2019.0, Cited 58.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. Recommanded Product: 100-51-6
The development of catalysts based on earth abundant metals in place of noble metals is becoming a central topic of catalysis. We herein report a cobalt/tetraphosphine complex-catalyzed homogeneous hydrogenation of polar unsaturated compounds using an air- and moisture-stable and scalable precatalyst. By activation with potassium hydroxide, this cobalt system shows both high efficiency (up to 24 000 TON and 12 000 h(-1) TOF) and excellent chemoselectivities with various aldehydes, ketones, imines, and even N-heteroarenes. The preference for 1,2-reduction over 1,4-reduction makes this method an efficient way to prepare allylic alcohols and amines. Meanwhile, efficient hydrogenation of the challenging N-heteroarenes is also furnished with excellent functional group tolerance. Mechanistic studies and control experiments demonstrated that a (CoH)-H-I complex functions as a strong hydride donor in the catalytic cycle. Each cobalt intermediate on the catalytic cycle was characterized, and a plausible outer-sphere mechanism was proposed. Noteworthy, external inorganic base plays multiple roles in this reaction and functions in almost every step of the catalytic cycle.
Recommanded Product: 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Duan, YN; Du, XY; Cui, ZK; Zeng, YQ; Liu, YF; Yang, TL; Wen, JL; Zhang, XM or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles