Product Details of 100-83-4. In 2020.0 CHEMISTRYSELECT published article about BIOLOGICAL EVALUATIONS; CHEMISTRY; EFFICIENT; HETEROCYCLES; FRAMEWORK; SOLVENT; ANALOGS; DESIGN in [Nazeef, Mohd; Tiwari, Saurabh Kumar; Yadav, Vikas; Ansari, Saif; Siddiqui, I. R.] Univ Allahabad, Lab Green Synth, Dept Chem, Allahabad 211002, Uttar Pradesh, India; [Saquib, Mohammad] Univ Allahabad, Dept Chem, Allahabad 211002, Uttar Pradesh, India; [Sagir, Hozeyfa] Paliwal PG Coll, Dept Chem, Shikohabad 283135, India; [Hussain, Mohd. Kamil] Govt Raza PG Coll, Dept Chem, Rampur 244901, India in 2020.0, Cited 46.0. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4.
A series of benzo[a]chromeno[2,3-c]phenazine derivatives were synthesized through an efficient one-pot, multicomponent eco-friendly reaction of 2-hydroxynaphthalene-1,4-dione, o-phenylenediamines, cyclic 1,3-dicarbonyl compounds and aromatic aldehydes, promoted by glycerol. To the best of our knowledge this is the first catalyst free protocol for synthesis of this important scaffold having potential applications in medicinal and materials chemistry. Other important attributes of the present method are the use of glycerol as a bio-renewable and biodegradable reaction medium-cum-promoter, use of readily available substrates, mild reaction conditions, operational simplicity, broad substrate scope, short reaction time, easy workup, and high yields and atom efficiency, which makes the disclosed protocol a superior alternative to existing methods.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles