Extracurricular laboratory:new discovery of 3-Indoleethanol

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Resonant Two-Photon Ionization Spectroscopic Analysis of Indole and Catechol Derivatives Using Pulsed Laser Desorption with Entrainment into Supersonic Jet Expansions

Pulsed laser desorption is used as a means of volatilizing thermally labile indole and catechol derivatives for entrainment into a supersonic jet expansion.The jet expansion provides ultracold molecules whose sharp spectral features are probed by resonant two-photon ionization (R2PI) spectroscopy in a time-of-flight mass spectrometer.Despite the structural similarity between many of the compounds studied herein, R2PI electronic spectrometry is shown to be a sensitive probe of small structural changes in these molecules and thus as a means of uniquely identifying each of these species.Target mixtures of various indole based compounds are studied under different conditions in order to establish the limitations to the selectivity of this technique.In addition, the limits of sensitivity are in the 10 pg range for these compounds and an optical spectrum can be obtained with as little as 300 ng of sample.

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Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles